OBJECTIVE: While mindfulness-based cognitive therapy (MBCT) has demonstrated efficacy in reducing depressive relapse/recurrence over 12-18 months, questions remain around effectiveness, longer-term outcomes, and suitability in combination with medication. The aim of this study was to investigate within a pragmatic study design the effectiveness of MBCT on depressive relapse/recurrence over 2...
Abstract By combining transcranial magnetic stimulation (TMS) with intravenous ketamine therapy, we sought to increase the therapeutic value of TMS and, at the same time, to improve the efficacy of intravenous ketamine therapy among depressed patients previously classified as non-responders. In this preliminary report, we provide evidence for a new and much more reliable method of treating...
PsychopharmacologyFebruary 2014Lynn Taurah, Chris Chandler, Geoff Sanders
Ecstasy (3,4-methylenedioxymethamphetamine, MDMA) is a worldwide recreational drug of abuse. Unfortunately, the results from human research investigating its psychological effects have been inconsistent. The present study aimed to be the largest to date in sample size and 5HT-related behaviors; the first to compare present ecstasy users with past users after an abstinence of 4 or more years,...
Cognitive bizarreness has been shown to be equally elevated in the dream and waking mentation of acutely symptomatic inpatients diagnosed with affective and non-affective psychoses. Although some studies have reported on dream content in non-psychotic depression, no study has previously measured this formal aspect of cognition in patients hospitalized for Psychotic Major Depression (PMD)....
CONTEXT: Workplace stress and burnout are pervasive problems, affecting employee performance and personal health. OBJECTIVE: To evaluate the effects of the Transcendental Meditation program on psychological distress and burnout among staff at a residential therapeutic school for students with severe behavioral problems. DESIGN: A total of 40 secondary schoolteachers and support staff at the...
The N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and potent antidepressant effects in treatment-resistant major depressive disorder and bipolar depression. These effects are in direct contrast to the more modest effects seen after weeks of treatment with classic monoaminergic antidepressants. Numerous open-label and case studies similarly validate ketamine's antidepressant...
The present study was conducted on the effect of mindfulness-based cognitive therapy (MBCT) on reduction of depression and Dysfunctional attitudes of divorced women in Tehran. It was an experimental study with pre-test-post-test design and control group. The population consists (100) individuals who answered the depression and dysfunctional attitudes questionnaires and 20 samples were chosen...
Mindfulness-based cognitive therapy (MBCT) is an integrative psychological approach linking mindful meditation with cognitive therapy. It has a strong evidence base in treating recurrent depression. However, limited research has been completed with older people. The present study evaluates one adapted, community based MBCT group (N=8) in a partial replication of Smith, Graham and Senthinathan...
The recreational drug MDMA (3,4-methylenedioxymethamphetamine) or 'Ecstasy' is associated with heightened psychiatric distress and feelings of depression. The Drugs and Infancy Study (DAISY) monitored the psychiatric symptom profiles of mothers who used Ecstasy/MDMA while pregnant, and followed them over the first year post-partum. We compared 28 young women whom took MDMA during their...