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Depression: all studies

Page 209 of 1,034: studies 2,081 to 2,090 of 10,336, newest first. Back to the depression overview

Research

The moderating and mediating roles of mindfulness and rumination on COVID-19 stress and depression: A longitudinal study of young adults.

Journal of counseling and psychology June 23, 2022 Jacob Schachter, Alex A. Ajayi, P. Nguyen

The COVID-19 pandemic has not only accounted for a substantial number of deaths in the United States but also deleterious mental health outcomes. We integrated multiple lines of previous research to better understand psychological strengths and difficulties in the face of the pandemic by testing a moderated mediation model that posited that rumination mediates the relationship between...

The Possible Application of Ketamine in the Treatment of Depression in Alzheimer’s Disease

Neurology International June 23, 2022 Islam Mohammad Shehata, Waniyah Masood, Nouran Nemr et al. 41 citations

Depression is a leading cause of disability globally, with a prevalence of 3.8% among the whole population, 5% of the adult population, and 5.7% of the elderly population over 60 years of age. There is evidence that depression is linked to certain neurodegenerative diseases, one being Alzheimer’s disease (AD). The efficacy of conventional antidepressants to treat depression in AD is...

Examining the interrelationships between mindfulness‐based interventions, depression, inflammation, and cancer survival

Ca June 16, 2022 D. Marinovic, Rebecca L. Hunter

Depression is highly prevalent in those diagnosed with cancer and is also associated with poorer prognostic outcomes. Mindfulness‐based interventions are effective in reducing depressive symptoms and improving quality of life in patients with cancer. The objective of this review was to investigate whether mindfulness practices can improve survival and, if so, what mechanisms of action may...

O uso da atenção plena como auxílio no tratamento de pensamentos automáticos que levam a depressão na adolescência / The use of mindfulness as an aid in the treatment of automatic thoughts that lead to depression in adolescence

Brazilian Journal of Development June 15, 2022 Marcus Solon Sá de Oliveira

Revisão sistemática sobre a eficácia da atenção plena como auxílio no tratamento de pensamentos automáticos em adolescentes. Problema da pesquisa: o que existe de pesquisas publicadas sobre o uso da atenção plena como auxílio no tratamento de pensamentos automáticos que levam a depressão em adolescentes? Objetivo: conhecer, mediante uma revisão sistemática de literatura, resultado de pesquisas...

Translational control by ketamine and its implications for comorbid cognitive deficits in depressive disorders

Journal of Neurochemistry June 9, 2022 Vern Lewis, Brandon Rodrigue, Emma J. Arsenault et al.

Ketamine has shown antidepressant effects in patients with major depressive disorder (MDD) resistant to first‐line treatments and approved for use in this patient population. Ketamine induces several forms of synaptic plasticity, which are proposed to underlie its antidepressant effects. However, the molecular mechanism of action directly responsible for ketamine's antidepressant effects...

Impact of Meditation–Based Lifestyle Modification on HRV in Outpatients With Mild to Moderate Depression: An Exploratory Study

Frontiers in Psychiatry June 9, 2022 Holger C Bringmann, Martin Bogdanski, Georg Seifert et al. 6 citations

Background The scientific evaluation of mind-body-interventions (MBI), including yoga and meditation, has increased significantly in recent decades. However, evidence of MBI's efficacy on biological parameters is still insufficient. Objectives In this study, we used HRV analysis to evaluate a novel MBI as a treatment of outpatients with mild to moderate depressive disorder. The Meditation-Based...

Psychedelic assisted therapy for major depressive disorder: Recent work and clinical directions

Journal of Psychedelic Studies June 9, 2022 Annie M. Mccartney, Hugh McGovern, Alexander de Foe 8 citations

Abstract Psychedelic substances such as psilocybin and ketamine may represent the future of antidepressant treatment, due to their rapid and prolonged effects on mood and cognition. The current body of psychedelic research has focused on administration and treatment within a psychiatric context. Here, instead, we put to the test the contention that it is necessary to evaluate the current state...

Clinical Significance of Stress, Depression, Anxiety, and Worry Symptom Improvement Following Mindfulness-based Stress Reduction

OBM Integrative and Complementary Medicine June 7, 2022 Holly Hazlett-Stevens

Mindfulness-based stress reduction (MBSR) teaches mindfulness meditation to reduce stress, anxiety, depression, and related forms of distress among a variety of patients. Much research has documented statistically significant reductions across a variety of self-report measures following MBSR, but researchers rarely assessed and reported the clinical significance of MBSR symptom reduction in...

Undertaking specific stress-reducing activities are associated with reduced fatigue and depression, and increased mastery, in people with multiple sclerosis.

Multiple sclerosis and related disorders June 2022 Nupur Nag, Xirun Yang, George Jelinek et al.

Multiple sclerosis is a demyelinating autoimmune disease, presenting with heterogenous symptoms that impact daily living. Undertaking stress-reducing activities may reduce symptoms including depression and fatigue, and enhance mastery, the sense of control of one's life. We assessed cross-sectional associations of undertaking stress-reducing activities or meditation on depression, fatigue, and...

(R)-ketamine as prophylactic and therapeutic drug for neurological disorders: beyond depression.

Neuroscience & Biobehavioral Reviews June 1, 2022 Xingming Wang, Jianjun Yang, Kenji Hashimoto

Neurological disorders are the leading cause of disability and the second leading cause of death worldwide. The increasing social and economic burdens of neurological disorders are driven by global population growth and aging. Depression is a common psychiatric symptom in numerous neurological disorders. It is also a risk factor for Alzheimer's disease (AD) and other dementias, Parkinson's...