This project is a systematic review that highlights how beneficial psychedelic psychotherapy can be to those suffering with mental illness. The three mental illnesses chosen to be analyzed in the literature were depression, post-traumatic stress disorder (PTSD), and anxiety. The drugs used in the specific articles included Psilocybin, Ayahuasca(DMT), and MDMA (3,4-methylenedioxymethamphetamine;...
Langlitz and colleagues wrote about clinically used psychedelic drugs and the possibility of a “moral psychopharmacology” earlier in this journal (1). They emphasized the context-dependency of the effects of these substances (e.g., ayahuasca, psilocybin) and the importance of understanding their impact on social and moral cognition, particularly now that there is more research on their possible...
Depression has long been recognized as a major public health problem.Fear and anxiety associated with the high morbidity and mortality of COVID-19 have increased risk factors for mental health decline.A high prevalence of psychiatric disorders has been documented in individuals who have been directly or indirectly exposed to life-threatening situations.Current evidence suggests decompensation...
Objetivo. Visibilizar las tensiones normativas que existen entre el derecho internacional de los derechos humanos y los tratados internacionales sobre control de drogas. Metodología. La fundación ICEERS creó el Ayahuasca Defense Fund (“ADF”), un programa que se encarga de la defensa legal de personas que enfrentan procesos penales por el uso de etnobotánicos. Para el presente análisis, se han...
Abstract The Indigenous cultures of South America developed a diverse array of traditional uses for psychoactive plants. This chapter surveys the historical and anthropological literatures on these practices. Pre-Columbian usage, later labeled as idolatry, was transformed by European colonization of the Americas. However, chroniclers such as Sahagun, Hernández, de Acosta, and Monardes, as well...
As we head into the (Northern Hemisphere) spring, the Journal publishes another set of papers which illustrate the robust health of the science of psychopharmacology. Once again, papers mostly focus on psychedelic drugs and related topics reflecting the zeitgeist (Young, 2022). de Wit et al. (2022) explore translational challenges and opportunities between clinical research and laboratory...
Back to table of contents Previous article Next article Ethics CornerFull AccessEthics Committees ReimaginedClaire Zilber, M.D.Claire Zilber, M.D.Published Online:28 Jan 2022https://doi.org/10.1176/appi.pn.2022.2.25The APA and district branch (DB) ethics committees used to stay busy processing complaints from patients, their family members, and colleagues about members who allegedly engaged in...
As with all drugs, the route, form, and/or dose of a substance administered or applied can play a defining role in its overall pharmacology and use as a therapeutic. This review will focus on these factors as they relate to the psychedelic N,N-dimethyltryptamine (DMT). It will examine the positive and negative aspects of different formulations and routes of administration of DMT and the...
Abstract Introduction There is an imminent need for faster-acting and more effective antidepressants beyond the monoaminergic hypothesis. Methods We systematically searched the US Clinical Trials registry for antidepressant compounds with completed phase II and III trials. Compounds that demonstrated significant superiority over placebo in the primary outcome measure in the latest phase of...
Abstract Rationale and objectives Differences among psychedelic substances regarding their subjective experiences are clinically and scientifically interesting. Quantitative linguistic analysis is a powerful tool to examine such differences. This study compared five psychedelic substance report groups and a non-psychedelic report group on quantitative linguistic markers of psychological states...