Grounded in Biology: Why the Context-Dependency of Psychedelic Drug Effects Means Opportunities, Not Problems for Anthropology and Pharmacology.
Frontiers in Psychiatry May 11, 2022 DOI: 10.3389/fpsyt.2022.906487 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Commentary Peer reviewed |
|---|---|
| Keywords | Embodiment Placebo Context-dependency Mind-body problem Psychedelics Psychedelic drugs 4e cognition |
| Citations | 16 |
| Key points | Argues that understanding clinically used psychedelics requires attention to context-dependency, examined here through placebo-effect research, and that "moral psychopharmacology" carries multiple meanings best clarified within a broader framework of drug instrumentalization and its associated values. The author distinguishes theoretical, research-oriented, and applied aspects to inform further theoretical, empirical, and ethical discussion. |
Abstract
Langlitz and colleagues wrote about clinically used psychedelic drugs and the possibility of a “moral psychopharmacology” earlier in this journal (1). They emphasized the context-dependency of the effects of these substances (e.g., ayahuasca, psilocybin) and the importance of understanding their impact on social and moral cognition, particularly now that there is more research on their possible clinical applications (e.g., to facilitate psychotherapy). In this opinion article, I want to, first, reflect on the context-dependency from the perspective of recent research on placebo effects, and, second, clarify different meanings of “moral psychopharmacology”. The latter will be placed in the context of a broader conceived view on drug instrumentalization (2–4) and different values associated with it (5–7). In the conclusion, I will briefly distinguish aspects primarily relevant to theoretical, research-oriented, or applied perspectives, respectively, to inform further theoretical, empirical, and ethical discussion of these topics.
Citations in the library
Cited by 10
- Harnessing placebo: Lessons from psychedelic science. Journal of Psychopharmacology June 30, 2023
- Keeping the promise: a critique of the current state of microdosing research Frontiers in Psychiatry February 5, 2024
- Ayahuasca-induced personal death experiences: prevalence, characteristics, and impact on attitudes toward death, life, and the environment Frontiers in Psychiatry December 19, 2023
- Therapeutic potential of psychedelics: History, advancements, and unexplored frontiers. Progress in Neuro-Psychopharmacology and Biological Psychiatry April 20, 2024
- Ethics of Psychedelic Use in Psychiatry and Beyond—Drawing upon Legal, Social and Clinical Challenges Philosophies August 24, 2023
and 5 more in the library
Cites 6
- Psychedelics and the essential importance of context. Journal of Psychopharmacology February 15, 2018
- Set and setting, psychedelics and the placebo response: An extra-pharmacological perspective on psychopharmacology Journal of Psychopharmacology November 16, 2016
- Transformative experience and social connectedness mediate the mood-enhancing effects of psychedelic use in naturalistic settings Proceedings of the National Academy of Sciences January 21, 2020
- The socialization of hallucinations: Cultural priors, social interactions, and contextual factors in the use of psychedelics. Transcultural Psychiatry October 1, 2022
- Set and Setting in the Santo Daime Frontiers in Pharmacology May 4, 2021
and 1 more in the library