Despite considerable efforts, tobacco use disorder persists as a significant public health issue. The effectiveness of current smoking cessation therapies is limited, leading to a growing interest in alternative treatment approaches such as psychedelics. The aim of this review is to evaluate the scientific evidence regarding the role of psychedelics in smoking cessation. To identify relevant...
This article provides an intercultural transdisciplinary perspective on the Indigenous roots of the resurging field of psychedelic science in the management of substance use disorders (SUDs). Ritual uses of entheogens (i.e., psychedelics of natural origin) are elaborate technologies for navigating, containing, and therapeutically directing non-ordinary states of consciousness induced by these...
SSRIs may not block the subjective or therapeutic effects of psychedelics, but more research is needed. MDMA is completely blocked by SSRIs and SNRIs, while ibogaine has strong QT prolonging effects and should not be combined with other QT prolonging drugs. Ayahuasca contains an MAOI and may cause serotonin syndrome if combined with antidepressants. Lithium and psychedelics may increase seizure...
Abstract Background Psychedelic use and its impact on well-being is garnering a lot of research attention, however, little has been done to understand the potential associations between multiple characteristics of the psychedelic experience and psychological flexibility (PF), which encompasses a conscious awareness of thoughts and behavior, allowing individuals to adapt to new experiences and...
Dimethyltryptamine (DMT), which is a psychedelic substance, has been a target of neuropharmacological research for years, mainly because of its potential use in the treatment of psychiatric disorders. The pineal gland is the best studied organ for endogenous DMT synthesis. At the same time, the role of DMT has not been clearly established. The association of the pineal gland with endogenous DMT...
When the Saskatchewan-based British psychiatrist Humphry Osmond first wrote to his fellow British émigré, novelist Aldous Huxley, he could have had little idea of how the ripples of their private correspondence of the early 1950s would reverberate across the world and into the future. But here we are in 2024, and the term that Osmond coined—‘psychedelic’—is quite literally everywhere, from...
Letras de HojeJuly 26, 2024Marcelo Marinho, Josemar De Campos Maciel, Anyie Lorena Cajamarca Torres
O presente exercício de prospecção de possíveis oikos vindouros, assentados na intersecção entre poesia e as assim chamadas “plantas de força”, centra-se na análise do campo lexical da espiritualidade que emerge em Fita verde no cabelo, breve narrativa publicada por Guimarães Rosa em suplemento literário do jornal O Estado de São Paulo, no dia 8 de fevereiro de 1964, sob fatura de inocente...
Abstract Background and aims Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research. This study extracts forum data on psychedelic substances, dosages, and administration routes, categorising and analysing self-reported consumption to inform care services and guide clinical work with...
AbstractBackground and aimsPsychedelics show promise for treatment of mental health conditions (MHCs). But there is relatively little research on indigenous psychedelics conducted in the Global South (GS). Much research is carried out in the Global North, where there are different cultural perceptions of mental health and psychedelics. Therefore, this paper appraises research on psychedelics...
5-MeO-DMT is a psychedelic substance with a short duration of action and intensive effects. Its therapeutic efficacy and practicality may significantly surpass those of classical psychedelics such as ayahuasca and LSD. This retrospective ethnographic inquiry features a woman in her mid-thirties who witnessed her mother's violent suicide and its bloody aftermath at the age of three. Before and...