Journal of Clinical Psychopharmacology
Vagner Deuel O de Tavares, Kaike Thiê da Costa Gonçalves, Maria Luiza de Morais Barros et al.
1 citation
In recent years, there has been a significant focus on exploring the potential therapeutic impact of altered states of consciousness on treatment outcomes for mental illness, with the goal of enhancing therapeutic strategies and patient results. This meta-analysis was designed to investigate the potential link between the psychomimetic effects of ketamine and clinical outcomes in mental health,...
American Journal of Therapeutics
Burton J. Tabaac, Kenneth Shinozuka, Alejandro Arenas et al.
14 citations
The primary psychoactive drug in magic mushrooms, psilocybin, induces profound alterations in consciousness through the 5-HT2A receptor. This review consolidates current research findings to elucidate the pharmacology, safety profile, and clinical applications of psilocybin. Despite initial concerns that psilocybin could cause psychosis, contemporary research has demonstrated that psilocybin is...
Clyde Mighells
preprint
Integrative Cognition Theory (ICT) proposes that consciousness is a fundamental, non-reductive property of the universe that is universally accessible, though its instantiation depends on the structural complexity and cognitive architecture of the substrate. Under this framework, Homo sapiens exhibit the most vivid expression of consciousness within the biological continuum, while non-human...
Paweł Gładziejewski, Aleksander Milczanowski, Bogna Bylicka et al.
preprint
Psychedelic substances can profoundly alter the experience of time, yet we lack a detailed account of which distinct temporal alterations occur, how prevalent they are, and how they are interrelated. A key obstacle is that the methods best suited to capturing the phenomenological repertoire of altered temporality are difficult to scale and may therefore fail to reliably capture rare phenomena,...
Stephanie J. Tepper
Research on flow, a positive emotional experience characterized by full absorption, involvement, and enjoyment during an activity, has primarily focused on the individual benefits of this mental state. In the present study, I investigate the mechanisms by which flow may produce changes in social orientation such that the boundaries between the self and other are diminished. In a 2x2 study,...
Vidushani Dhanawansa, Devon Stoliker, Leonardo Novelli et al.
Background: Psilocybin is a serotonergic psychedelic that provides a pharmacological tool for examining neural activity associated with altered states of consciousness. Existing studies report reduced power (4-30 Hz) in posterior regions and altered functional connectivity (FC) at rest, but have typically involved small samples and coarse anatomical parcellations. Additionally, perceptual...
Parsa Yousefi, Kenneth Shinozuka, Patrick Vizeli et al.
Psychoactive drugs profoundly alter consciousness, but the neural mechanisms by which they do so remain poorly understood. Global workspace theory may provide a framework for investigating these mechanisms. The global workspace, a candidate neural substrate of consciousness, is a set of brain regions that integrate and disseminate information to the rest of the brain. According to a recent...
Raquel Rodríguez‐carvajal, Óscar Lecuona, Luz Sofía Vilte et al.
Music performing usually binds intense psychological experiences, from which music performance anxiety (MPA) is amongst the most damaging and pervasive ones. Alongside, some constructs seem to be associated with MPA, like negative affect and self-consciousness. In the interaction between these three elements, mindfulness seems to be an effective tool to cope with MPA by altering the...
Denis Larrivee, Diane Steele
From pharmacological manipulation to interfacial neurotechnologies, approaches to neuroenhancement span a broad and expanding technology spectrum. Many such procedures introduce profound changes in brain function, oftentimes with serious health risks. The Presidential Commission for the study of Bioethical issues (Gray Matters II, 2015), by contrast, has recommended enhancement protocols that...
Graham Nicholls, Luciano Pederzoli, Patrizio Tressoldi
The aim of this paper is to compare the exteroception and general phenomenology of naturally arising, or spontaneous out-of-body experiences (OBEs), sometimes also referred to as extra-corporeal experiences (ECEs) with those that have been induced via the use of hypnotic induction in order to compare their phenomenology. The similarities and differences emerged from this comparison offer a very...