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Effect of Combined Music Therapy and Mindfulness-Based Stress Reduction on Patients with Uterine Adenomyosis Following HIFU Treatment.

JinJin Yang, Ya Chen

Noise & health December 31, 2025 DOI: 10.4103/nah.nah_139_25 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Retrospective study Peer reviewed
Sample size 146
Population Patients with uterine adenomyosis after high-intensity focused ultrasound (HIFU) ablation, admitted January to December 2024
Interventions Music therapy Mindfulness-based stress reduction
Duration Assessed on postoperative Day 3 and 14 days after care
Measures Visual Analogue Scale (VAS), Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS), Pittsburgh Sleep Quality Index (PSQI), EuroQol Five Dimensions Questionnaire (EQ-5D)
Topics Meditation
Keywords Mindfulness-based stress reduction Music therapy Treatment outcome Uterine adenomyosis
Key points Adding music therapy to mindfulness-based stress reduction was associated with lower pain scores on postoperative Day 3 and lower depression, anxiety, and sleep-quality scores 14 days after care compared with mindfulness-based stress reduction alone. Quality-of-life utility values were higher in the combined group (0.602 vs 0.437), with reported improvements in self-care and anxiety/depression.

Abstract

To investigate the effects of music therapy combined with mindfulness-based stress reduction on psychological state, pain and sleep in patients with uterine adenomyosis after high-intensity focused ultrasound (HIFU) ablation. A retrospective study was conducted on 146 adenomyosis patients admitted from January 2024 to December 2024. In accordance with nursing methods, patients were assigned to the mindfulness group (n = 68), which received mindfulness-based stress reduction care, or the combined group (n = 78), which received music therapy plus mindfulness-based stress reduction. Clinical data, visual analogue scale (VAS) scores, Self-rating Depression Scale (SDS) scores, Self-rating Anxiety Scale (SAS) scores, Pittsburgh Sleep Quality Index (PSQI) scores and EuroQol Five Dimensions Questionnaire (EQ-5D) scores were compared. On postoperative Day 3, the VAS scores were significantly lower in the combined group (P < 0.05), and 14 days after care, the SDS, SAS and PSQI scores were all lower than those of the mindfulness group. EQ-5D analysis revealed significant improvements in self-care and anxiety/depression in the combined group (P < 0.05). Utility values were 0.437 ± 0.153 in the mindfulness group and 0.602 ± 0.161 in the combined group (P < 0.05). Music therapy with mindfulness-based stress reduction improves anxiety management, self-care, quality of life and recovery in postoperative HIFU patients with adenomyosis and alleviates pain.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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