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Effects of a Mindfulness-Based Stress Reduction Program on Stress, Depression, and Psychological Well-being in Patients With Cancer: A Single-Blinded Randomized Controlled Trial.

Dilek Yıldırım, Cennet Çiriş Yildiz, Ferda Akyuz Ozdemir, Merve Harman Özdoğan, Gulbeyaz Can

Cancer Nursing December 11, 2022 DOI: 10.1097/ncc.0000000000001173 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Single-blinded, prospective, randomized controlled trial Peer reviewed
Sample size 120
Population Adult patients with cancer
Intervention Mindfulness-based stress reduction program combined with music therapy
Duration 10-day program, measured at baseline and 10 days
Measures State Trait Anxiety Inventory-State, Psychological Well-being Scale, Beck Depression Inventory
Topics Depression Meditation
Key findings A 10-day online mindfulness-based stress reduction program combined with music therapy significantly reduced stress and depression scores and significantly improved psychological well-being compared with a control group at 10 days; within the intervention group, stress and depression scores fell significantly from pretest to posttest. The authors propose this nurse-led program as an effective psychological intervention that may be integrated into regular cancer care.

Abstract

A mindfulness-based stress reduction program combined with music therapy is one of the interventions designed to help patients cope with stress and depression. The aim of this study was to examine the effects of an online mindfulness-based stress reduction program combined with music therapy on stress, depression, and psychological well-being in adult patients with cancer. This study was a single-blinded, prospective, randomized-controlled experimental design. One hundred twenty cancer patients were recruited (60 each in the intervention and control groups). Patients in the intervention group received a 10-day mindfulness-based stress reduction program combined with music therapy. Stress was measured with the State Trait Anxiety Inventory-State, psychological well-being was measured with the Psychological Well-being Scale, and depression was measured with the Beck Depression Inventory at baseline and the end of the study. The intervention group showed significantly lower stress and depression scores than the control group in the total scores at 10 days ( P < .05). The intervention group had significantly higher scores in the psychological well-being ( P < .001) than the control group at 10 days. Intragroup comparison of the stress and depression scores showed that posttest score of the intervention group was significantly lower than its pretest score ( P < .05). Mindfulness-based stress reduction program combined with music therapy reduced the levels of stress and depressive symptoms and improved psychological well-being in cancer patients. A nurse-led mindfulness-based stress reduction program combined with music therapy is an innovative and effective psychological intervention that may be integrated with regular patient care for adults receiving treatment of cancer.

Comparable studies

Other randomized controlled trials on depression, most cited first.

Study Year Design Participants
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression Subjects with DSM-IV major depression (treatment resistant) 2006 Randomized, placebo-controlled, double-blind crossover study n = 18
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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Depression Meditation Anxiety