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Brief Interactive Virtual Reality Mindfulness Training with Real-Time Biofeedback for Anxiety Reduction: A Pilot Study.

Qiuxia Xu, Yingqi Gu, Xizhe Hu

Applied Psychophysiology and Biofeedback June 4, 2025 DOI: 10.1007/s10484-025-09718-w (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Pilot study Peer reviewed
Sample size 75
Population University students with recent anxiety symptoms
Intervention Traditional audio-based mindfulness
Duration Single five-minute session
Topics Anxiety Meditation
Keywords Biofeedback Brief mindfulness intervention Heart rate variability Virtual reality Vr Immersive technology Digital environment Simulated reality Mental well-being Inner peace Calmness Stress management Anxiety reduction Stress relief Emotional regulation Mental health improvement Well-being enhancement Physiological monitoring Biometric feedback Real-time data
Citations 5
Key findings A five-minute interactive VR mindfulness session significantly improved anxiety, mindfulness states, and heart rate variability compared to traditional mindfulness and a control condition.

Abstract

Recent advancements in virtual reality (VR)-enhanced mindfulness training have demonstrated efficacy in reducing anxiety, particularly among novice practitioners and university students. However, existing VR mindfulness interventions predominantly rely on static natural environments without incorporating interactive elements, limiting their capacity to engage users dynamically. To address this gap, this study introduces an innovative interactive VR mindfulness system, where real-time heart rate variability (HRV) biofeedback dynamically modulates the virtual environment (e.g., fog dissipation, auditory cues, and visual transformations), creating a responsive and immersive experience. We investigated the effects of a single five-minute interactive VR mindfulness session on anxiety, mindfulness states, and HRV, compared to traditional audio-based mindfulness and an non-intervention control. Seventy-five university students with recent anxiety symptoms were randomized into three groups: interactive VR mindfulness (VR-MG), traditional mindfulness (MG), and control (CG). Prior to and following the five-minute intervention, anxiety, mindfulness levels, and physiological data (HRV) were measured for all three groups, with repeated measures analysis of variance performed. The results showed that the five-minute VR mindfulness interactive training significantly improved participants' anxiety levels, enhanced their mindfulness states, and effectively increased HRV, whereas traditional mindfulness and control conditions showed no significant HRV changes. Overall, this study indicates that brief VR mindfulness interactive training has significant effects on improving anxiety and mindfulness states, as well as enhancing HRV, highlighting its potential for psychological health interventions.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

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