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Long-term endocrinologic changes in subjects practicing the Transcendental Meditation and TM-Sidhi program.

O R Werner, R K Wallace, B Charles, G Janssen, T Stryker, R A Chalmers

Psychosomatic Medicine 1986 DOI: 10.1097/00006842-198601000-00004 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Prospective longitudinal observational study Peer reviewed
Sample size 11
Population Male subjects starting the TM-Sidhi program
Interventions Transcendental Meditation TM-Sidhi program
Duration 3-year follow-up after starting the TM-Sidhi program
Topics Meditation
Key findings Over three years after starting the TM-Sidhi program, serum TSH, growth hormone, and prolactin decreased progressively, while cortisol, T4, and T3 showed no consistent change. The authors suggest long-term Transcendental Meditation and TM-Sidhi practice may affect neuroendocrine function, but state that further study with 24-hour frequent blood sampling is needed.

Abstract

The Transcendental Meditation (TM) and a more advanced program, the TM-Sidhi program, have been reported to produce a number of acute and long-term metabolic and electrophysiologic changes. To investigate the possibility that the practice of these techniques may be associated with long-term endocrinologic changes, we prospectively evaluated 11 male subjects before and over a 3-year period after starting the TM-Sidhi program. A progressive decrease in serum TSH, growth hormone, and prolactin levels occurred over the 3 years while no consistent change in cortisol, T4, or T3 levels was observed. These results suggest that the long-term practice of the TM and TM-Sidhi program may have effects on neuroendocrine function. Further studies using 24-hr monitoring with frequent blood sampling will, however, be needed to fully assess the significance of the simultaneous decline of the anterior pituitary hormones with maintenance of levels of hormones from peripheral endocrine glands.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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