Effects of mindfulness meditation combined with progressive muscle relaxation on sleep disorders, anxiety, and depression in patients with sarcopenia undergoing hemodialysis.
Yongyao Wu, Haojie Zhang, Lei Jiang, Zhiping Liu, Xinfei Li, Bei Guo, Junyuan Li, Pengjie Xu, Jiang Liu, Rizhen Yu
Frontiers in Psychiatry 2025 DOI: 10.3389/fpsyt.2025.1542028 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 49 |
| Population | Maintenance hemodialysis patients with uremic sarcopenia and sleep issues |
| Interventions | Mindfulness meditation progressive muscle relaxation |
| Duration | 12-week intervention |
| Topics | Anxiety Depression Meditation |
| Keywords | Hemodialysis Mindfulness meditation Progressive muscle relaxation Sleep disorders Uremic sarcopenia Mindfulness-based intervention Mental health |
| Citations | 8 |
| Registration | NCT06261372 |
| Key findings | Mindfulness meditation combined with progressive muscle relaxation significantly improved sleep quality, reduced anxiety and depression, and increased quality of life in hemodialysis patients with sarcopenia. |
Abstract
Long-term physiological, psychological, economic, and lifestyle pressures make maintenance hemodialysis (MHD) patients prone to anxiety and depression. This study aims to evaluate the effects of mindfulness meditation combined with progressive muscle relaxation on sleep and emotional disorders in hemodialysis patients with sarcopenia. Patients with uremic sarcopenia and sleep issues were randomly divided into a control group (n=24) and an intervention group (n=25), with an average age of 45.4 ± 4.77 years and an average dialysis duration of 56.86 ± 17.48 months. The control group received standard treatment (hemodialysis three times per week, medication, health education, dietary guidance, and exercise recommendations), while the intervention group additionally underwent home-based mindfulness and relaxation training for at least 0.5 hours daily over 12 weeks. Sleep quality, emotional states, and quality of life were assessed using the Pittsburgh Sleep Quality Index (PSQI), Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), and 36-Item Short Form Health Survey (SF-36). Data analysis included descriptive statistics, t-tests, analysis of covariance, Mann-Whitney U tests, and chi-square tests. Before the intervention, there were no significant differences between the two groups in sleep, anxiety, depression, or quality of life (P>0.05). After the intervention, the intervention group showed significant improvements in all PSQI dimensions (e.g., sleep medication use, sleep quality, and sleep duration) (P<0.01), significant reductions in SAS and SDS scores (P<0.05), and significantly higher SF-36 scores compared to the control group (P<0.05). Mindfulness and muscle relaxation training can alleviate psychological stress, reduce skeletal muscle tension, promote muscle anabolism, and significantly improve sleep quality, anxiety, and depression in hemodialysis patients with sarcopenia. This approach is simple, unrestricted, and widely applicable, making it worthy of clinical promotion. The study had a small sample size and a short follow-up period. https://register.clinicaltrials.gov/, identifier NCT06261372.
Comparable studies
Other randomized controlled trials on anxiety, most cited first.
Citations in the library
Cites 9
- How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective Perspectives on Psychological Science October 14, 2011
- Mindfulness Meditation and Psychopathology Annual Review of Clinical Psychology December 11, 2018
- A Randomized Controlled Trial of Mindfulness Meditation for Chronic Insomnia Sleep August 29, 2014
- Levels of immune cells in transcendental meditation practitioners International Journal of Yoga 2014
- The influence of mindfulness meditation combined with progressive muscle relaxation training on the clinical efficacy and quality of life of patients with sarcopenia receiving haemodialysis: a randomised controlled trial. BMC Complementary Medicine and Therapies May 17, 2024
and 4 more in the library