Neuroscience: Modeling the Brain on Acid.
Johan Van der Meer, Michael Breakspear
Current Biology October 8, 2018 DOI: 10.1016/j.cub.2018.08.008 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or computational modeling paper Peer reviewed |
|---|---|
| Intervention | LSD |
| Key points | Proposes that integrating a serotonin receptor distribution map into a model of dynamic brain activity under LSD can help explain experimental manipulations of healthy brain activity and provide a new drug-discovery platform. |
Abstract
A receptor map of serotonin distribution is integrated into a model of the dynamic activity of the brain under the effects of LSD. The approach opens new avenues to understand experimental manipulations of healthy brain activity and offers a novel drug-discovery platform.
Citations in the library
Cites 3
- Ongoing Cortical Activity at Rest: Criticality, Multistability, and Ghost Attractors Journal of Neuroscience March 7, 2012
- Crystal structure of an LSD-bound human serotonin receptor Cell January 26, 2017
- Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD. Current Biology September 27, 2018