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[Basic symptoms in schizophrenia, their clinical study and relevance in research].

Salvador Miret, Mar Fatjó‐Vilas, Víctor Peralta, Lourdes Fañanás

Revista de psiquiatria y salud mental 2016 DOI: 10.1016/j.rpsm.2015.10.007 (opens in new tab)

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AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Philosophy of mind
Keywords Basic symptoms Esquizofrenia Fase prodrómica Fenomenología Instrumentos Instruments Prodromal phase Schizophrenia Síntomas básicos
Key findings Argues that basic symptoms—subtle, subjectively experienced sub-clinical disturbances in domains such as drive, affect, thinking, perception, and stress tolerance—are among the earliest features of schizophrenia and can evolve over its course. Assessed during the prodromal phase together with ultra-high risk criteria, they constitute one of the two main approaches for defining clinical risk states for psychosis, and the authors propose they may help establish neurobiological correlates for aetiopathogenic research.

Abstract

Basic symptoms consist of subtle sub-clinical disturbances subjectively experienced by schizophrenia patients. These are mainly related to drive, affect, thinking and language, perception, memory, motor action, central vegetative functions, control of cognitive processes, and stress tolerance. Initially described by Huber, from a phenomenological approach, basic symptoms are part of the earliest features of schizophrenia, and they can evolve along the course of the disorder. Their assessment during the prodromal phase of the disease (together with ultra-high risk criteria) is one of the 2 main approaches that allow the definition of states of clinical risk for the development of psychosis. The present review provides an updated view of the concept of basic symptoms, highlighting its potential value in establishing neurobiological correlates of interest in aetiopathogenic research.

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