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Assessing the Effects of Mindfulness-Based Intervention on Anxiety and Cortisol in Pregnancy

Finta Isti Kundarti, I Nengah Tanu Komalyna, Ira Titisari, Kiswati Kiswati, Jamhariyah Jamhariyah

Universal Journal of Public Health October 1, 2023 DOI: 10.13189/ujph.2023.110524 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 70
Population Pregnant women
Duration 8 weeks, 2 hours per session; assessments at baseline and end of week 8
Measures Perinatal Anxiety Screening Scale (PASS), ELISA test for blood cortisol
Topics Anxiety Meditation
Citations 1
Key findings Pregnant women who received an 8-week mindfulness-based intervention had significantly lower mean anxiety scores (12.83 vs 30.69) and lower mean blood cortisol levels (14.30 vs 19.51) than controls at posttest. The authors conclude that MBI can be suggested to reduce anxiety and blood cortisol levels in pregnant women.

Abstract

Introduction: The perinatal period is a transitional period for pregnant women in terms of physiological, psychological, and social changes. These changes cause anxiety during pregnancy. Mindfulness-based intervention is a new intervention that can help reduce anxiety during pregnancy and cortisol is a biomarker of stress or anxiety. The purpose of this research was to determine the degree of anxiety and blood cortisol levels in pregnant women. Patients and

Methods: This research used a Randomized control study involving 70 participants which was split into two groups, with intervention group using MBI (n = 35 participants) and the control group without MBI (n = 35 respondents). The MBI was given over 8 weeks for 2 hours each session. Data collection on anxiety and blood cortisol was carried out 2 times, namely at the beginning of the study (pretest) and at the end of the 8th week (posttest). Anxiety assessment used the perinatal anxiety screening scale (PASS) and the ELISA test to assess blood cortisol. SPSS 25 was also used to analyze the data.

Results: In terms of anxiety, there was a statistically significant difference in mean scores between the intervention group and the control group (12.83±8.29 vs 30.69±16.39) P < 0.000, cortisol (14.30±5.29 vs 19.51±8.46) p=0.003.

Conclusion: MBI can be suggested to promote reduction of anxiety and blood cortisol levels of pregnant women.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

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