A critical analysis of lysergic acid diethylamide in the present light!
M. Baskaran, Saravanan Mani, T. Maheswari, S. Muthulakshmi, A. Jayasudha
International Journal of Advanced Psychiatric Nursing 2020 DOI: 10.33545/26641348.2020.v2.i1a.23 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | LSD |
| Key findings | Argues that LSD's history moved from psychiatric research tool to prohibited drug with no accepted clinical use, and that its pharmacology and receptor and gene-expression effects justify further investigation of its potential as a treatment for addictions. |
Abstract
Lysergic acid diethylamide (LSD) is a semisynthetic compound with solid psychoactive properties. Chemically related to serotonin LSD was initially hypothesized to produce a psychosis-like state.1 Afterward, LSD was accounted for to have benefits in the treatment of addictions. However, far reaching unpredictable use and reports of unfriendly impacts brought about the arrangement of LSD as an illegal medication with no acknowledged clinical use. This article audits LSD's celebrated history from its disclosure, to its utilization as an exploration instrument, trailed by it across the board relationship with the counterculture development of the 1960s, lastly to its resurrection as a medication with expected advantages in the treatment of addictions. LSD's pharmacology, phenomenology, impacts at synapse receptors, and consequences for examples of quality articulation are looked into. In view of a survey of the writing, it is reasoned that further examination into LSD's potential as a treatment for addictions is justified.
Comparable studies
Other narrative reviews on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Study of a New Schizophrenomimetic Drug—Sernyl | 1959 | Review | |
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| The Pharmacology of Lysergic Acid Diethylamide: A Review | 2008 | Review | |
| Serotonin research: contributions to understanding psychoses | 2008 | Review | |
| ADVERSE REACTIONS TO PSYCHEDELIC DRUGS. A REVIEW OF THE LITERATURE | 1984 | Review |
Citations in the library
Cites 2
- Decreased mental time travel to the past correlates with default-mode network disintegration under lysergic acid diethylamide Journal of Psychopharmacology 2016
- A Review of Lysergic Acid Diethylamide (LSD) in the Treatment of Addictions: Historical Perspectives and Future Prospects Current Drug Abuse Reviews January 9, 2015