Skip to content

Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder.

Sang-Hyuk Lee, Seung Chan Ahn, Yu Jin Lee, Tae Kyu Choi, Ki Hwan Yook, Shin Young Suh

Journal of Psychosomatic Research February 2007 DOI: 10.1016/j.jpsychores.2006.09.009 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Population Patients with anxiety disorder
Interventions Meditation-based stress management program Anxiety disorder education program
Duration 8-week program, with outcome measured at 0, 2, 4, and 8 weeks
Measures Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale (HAM-D), State-Trait Anxiety Inventory (STAI), Beck Depression Inventory, Symptom Checklist-90-Revised (SCL-90-R)
Topics Anxiety Meditation
Key findings Patients with anxiety disorder assigned to an 8-week meditation-based stress management program showed significantly greater improvement than an education group on all anxiety scales (HAM-A, STAI state, STAI trait, SCL-90-R anxiety) and on the SCL-90-R hostility subscale, while depression results were inconsistent and several other SCL-90-R subscales showed no significant improvement. The authors argue the program may be effective for anxiety symptoms but needs further randomized controlled trials before clinical use.

Abstract

The objective of this study was to examine the effectiveness of a meditation-based stress management program in patients with anxiety disorder. Patients with anxiety disorder were randomly assigned to an 8-week clinical trial of either a meditation-based stress management program or an anxiety disorder education program. The Hamilton Anxiety Rating Scale (HAM-A), the Hamilton Depression Rating Scale (HAM-D), the State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory, and the Symptom Checklist--90-Revised (SCL-90-R) were used to measure outcome at 0, 2, 4, and 8 weeks of the program. Compared to the education group, the meditation-based stress management group showed significant improvement in scores on all anxiety scales (HAM-A, P=.00; STAI state, P=.00; STAI trait, P=.00; anxiety subscale of SCL-90-R, P=.00) and in the SCL-90-R hostility subscale (P=.01). Findings on depression measures were inconsistent, with no significant improvement shown by subjects in the meditation-based stress management group compared to those in the education group. The meditation-based stress management group did not show significant improvement in somatization, obsessive-compulsive symptoms, and interpersonal sensitivity scores, or in the SCL-90-R phobic anxiety subscale compared to the education group. A meditation-based stress management program can be effective in relieving anxiety symptoms in patients with anxiety disorder. However, well-designed, randomized, and controlled trials are needed to scientifically prove the worth of this intervention prior to treatment.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

Citations in the library

Cited by 29

and 24 more in the library

Cites 6

and 1 more in the library

Explore topics