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Meditation improves clinicoelectroencephalographic measures in drug-resistant epileptics.

K K Deepak, S K Manchanda, M C Maheshwari

Biofeedback and self-regulation March 1994 DOI: 10.1007/bf01720668 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Controlled trial with waiting-list control group Peer reviewed
Sample size 20
Population Adults with drug-resistant epilepsy taking antiepileptic drugs
Intervention Meditation
Dose 20 minutes a day
Duration One year
Topics Meditation
Key findings Adults with drug-resistant epilepsy who practiced meditation 20 minutes daily for one year showed significant reductions in seizure frequency and duration and changes in EEG spectral measures, while waiting-list controls showed no significant changes in seizure frequency or duration. The authors conclude that continued meditation practice is of substantial help in improving the clinical and electrographic picture in this population.

Abstract

Eleven adults suffering from drug-resistant epilepsies were given meditation practice, while another nine adults acted as waiting list controls. All patients were on antiepileptic drugs and their serum drug levels were monitored regularly. Patients in the intervention group were given training in meditation, and they practiced meditation 20 minutes a day for one year. They showed a significant reduction in seizure frequency and duration, an increase in the dominant background EEG frequency, a reduction in mean spectral intensity of the 0.7-7.7 Hz segment, and an increment in mean spectral intensity in the 8-12 Hz segment of the EEG. All changes were statistically significant. Control patients did not show significant changes in seizure frequency and duration during the observation period of one year. The results indicate that continued meditation practice is of substantial help in improving the clinicoelectrographic picture in drug-resistant epileptics.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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