Skip to content

Mindfulness- and acceptance-based interventions for anxiety disorders: a systematic review and meta-analysis.

Jon Vøllestad, Morten Birkeland Nielsen, Geir Høstmark Nielsen

British Journal of Clinical Psychology September 2012 DOI: 10.1111/j.2044-8260.2011.02024.x (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Peer reviewed
Population Patients diagnosed with anxiety disorders
Intervention Mindfulness- and acceptance-based interventions (MABIs)
Topics Anxiety Meditation
Key findings Across 19 studies, mindfulness- and acceptance-based interventions were associated with large within-group reductions in anxiety (Hedges' g = 1.08) and depression symptoms (g = 0.85), and moderate between-group effects versus controls (g = 0.83 for anxiety, g = 0.72 for depression). The authors report that adding specific psychotherapeutic content and individual treatment were associated with larger effects, and conclude that more research is needed to compare these interventions with current treatments of choice.

Abstract

Mindfulness- and acceptance-based interventions (MABIs) are receiving increasing attention in the treatment of mental disorders. These interventions might be beneficial for patients with anxiety disorders, but no prior reviews have comprehensively investigated the effects of this family of interventions on clinical samples. The aim of this study was to review and synthesize extant research on MABIs for patients with diagnoses of anxiety disorders. We conducted a systematic search of relevant databases according to pre-defined criteria. Studies were eligible for inclusion if they employed MABIs for patients diagnosed with anxiety disorders. Nineteen eligible studies were found. Meta-analysis of within-group pre- to post-treatment effects yielded overall Hedges'g effect sizes of 1.08 for anxiety symptoms and 0.85 for depression symptoms. For controlled studies, overall between-group Hedges'g was 0.83 for anxiety symptoms and 0.72 for depression symptoms. Moderator analyses examined whether intervention type, design, treatment dosage, or patient sample was associated with systematic variation in effect sizes. No significant moderating effects were found on the variables examined, apart from an observed superiority in effect size for clinical trials on samples of patients with mixed anxiety disorders. However, differential effect sizes indicated benefits of adding specific psychotherapeutic content to mindfulness training, as well as an advantage of individual over group treatment. MABIs are associated with robust and substantial reductions in symptoms of anxiety and comorbid depressive symptoms. More research is needed to determine the efficacy of MABIs relative to current treatments of choice, and to clarify the contribution of processes of mindfulness and acceptance to observed outcome.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

Citations in the library

Explore topics