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Psychoactive tryptamines from basidiomycetes.

M Wurst, R Kysilka, M Flieger

Folia microbiologica 2002 DOI: 10.1007/bf02818560 (opens in new tab)

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Characteristics Review Peer reviewed
Keywords Humans Basidiomycota Tryptamines Hallucinogens Psychotropic drugs History, ancient History, 16th century History, 17th century History, 20th century
Key findings The review compiles the natural sources, chemistry, toxic and psychological effects, biosynthesis, and analytical and isolation methods for psychoactive tryptamines from fungi, including mycelial cultures of Psilocybe bohemica Sebek, and assesses worldwide and Czech use and abuse of psychoactive fungi as drug sources over the last two and a half decades.

Abstract

The review lists natural sources, i.e. strains and species of fungi producing predominantly psychoactive tryptamines (indolealkylamines), their chemical structure and properties, toxic effects on the man and psychic symptoms of intoxication. It describes the biosynthesis and production of some tryptamines by the mycelial culture of Psilocybe bohemica Sebek, a survey of methods for their analysis and isolation. It evaluates the worldwide use and abuse of psychoactive fungi as sources of drugs in general and in the Czechia in particular during the last two and a half decades.

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