Psychosis in Parkinson's Disease: Phenomenology, Frequency, Risk Factors, and Current Understanding of Pathophysiologic Mechanisms
CNS Spectrums March 1, 2008 DOI: 10.1017/s1092852900017284 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Population | Patients with Parkinson's disease |
| Topics | Philosophy of mind |
| Key findings | The review states that psychosis in Parkinson's disease most commonly involves complex visual hallucinations, with "minor" hallucinatory phenomena frequently present, while paranoid delusions are rarer. Hallucinations and delusions are more frequent in patients with dementia, and the authors describe pathogenesis as complex and probably multifactorial, involving dopaminergic treatment and disease-related factors. |
Abstract
ABSTRACT: Psychosis in Parkinson's disease refers to a combination of hallucinations and delusions occurring with a clear sensorium and a chronic course. Hallucinations may involve several sensory modalities. Complex visual hallucinations are the most common type. “Minor” hallucinatory phenomena are frequently present and include visual illusions, passage hallucinations, and sense of presence. Insight may be lost in patients with cognitive impairment. Delusions of a paranoid type are more rare than hallucinations. Both hallucinations and delusions are more frequent in Parkinson's disease patients with dementia. Pathogenesis involves complex and probably multifactorial mechanisms, including pharmacologic (dopaminergic treatment and others) and disease-related factors.
Comparable studies
Other narrative reviews on philosophy of mind, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Body Consciousness: A Philosophy of Mindfulness and Somaesthetics | 2008 | Review article | |
| Phenomenology, Structure, and Dynamic of Psychedelic States | 2016 | Review | |
| Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates. | 2018 | Review | |
| The lived experience of psychosis: a bottom-up review co-written by experts by experience and academics. Individuals with lived experience of psychosis, family members, and carers | 2022 | Co-written bottom-up review | |
| From autopoiesis to neurophenomenology: Francisco Varela's exploration of the biophysics of being. | 2003 | Review |
Citations in the library
Cited by 2
Cites 2
- Repeated visual hallucinations in Parkinson's disease as disturbed external/internal perceptions: focused review and a new integrative model. Movement Disorders February 2005
- Acetylcholine and hallucinations: disease-related compared to drug-induced alterations in human consciousness. Brain and Cognition August 1, 1995