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What is the function of the claustrum?

Francis C. Crick, Christof Koch

Philosophical transactions of the Royal Society of London. Series B, Biological sciences June 1, 2005 DOI: 10.1098/rstb.2005.1661 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Keywords Basal ganglia Interneurons Humans Consciousness Models, neurological
Key findings Argues that the claustrum, a thin sheet-like structure receiving input from and projecting back to almost all cortical regions, may be involved in the processes that give rise to integrated conscious percepts, and proposes mechanisms for wide information travel within it along with experiments to test these questions.

Abstract

The claustrum is a thin, irregular, sheet-like neuronal structure hidden beneath the inner surface of the neocortex in the general region of the insula. Its function is enigmatic. Its anatomy is quite remarkable in that it receives input from almost all regions of cortex and projects back to almost all regions of cortex. We here briefly summarize what is known about the claustrum, speculate on its possible relationship to the processes that give rise to integrated conscious percepts, propose mechanisms that enable information to travel widely within the claustrum and discuss experiments to address these questions.

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