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Dispositional mindfulness and prescription opioid misuse among chronic pain patients: Craving and attention to positive information as mediating mechanisms.

Sarah E. Priddy, Adam W. Hanley, Michael R. Riquino, Keith A Platt, Anne Baker, Eric L Garland

Drug and Alcohol Dependence July 1, 2018 DOI: 10.1016/j.drugalcdep.2018.03.040 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional observational study Peer reviewed
Sample size 300
Population Civilian and military opioid-treated chronic pain patients in the Southeastern and Intermountain West regions of the U.S.
Measures Current Opioid Misuse Measure (COMM), Five Facet Mindfulness Questionnaire (FFMQ), Attention to Positive and Negative Information Scale (APNIS)
Topics Meditation
Keywords Chronic pain Natural reward Opioid craving Opioid misuse
Key findings Across three samples of opioid-treated chronic pain patients, dispositional mindfulness was inversely associated with opioid misuse (N = 300, r = -0.36). The authors report that reduced opioid craving and increased attention to positive information mediated this relationship, suggesting mindfulness may buffer misuse risk by attenuating craving and enhancing attention to natural rewards.

Abstract

Opioid-treated chronic pain patients may be at risk for prescription opioid misuse due to heightened opioid craving coupled with deficits in attention to naturally rewarding, positive stimuli. Conversely, dispositional mindfulness, which is associated with reduced craving and increased responsiveness to natural rewards, may serve as a protective factor and buffer opioid misuse risk. The current investigation aimed to examine the association between mindfulness and opioid misuse, and to test opioid craving and attention to positive information as mediators of this relationship. This cross-sectional analysis examined data obtained from a sample of civilian opioid-treated chronic pain patients in the Southeastern U.S. (Sample 1: N = 115), as well as civilian (Sample 2: N = 141) and military samples in the Intermountain West (Sample 3: N = 44). Pearson correlations and path analyses were employed to test relations among participant self-reports on the Current Opioid Misuse Measure (COMM), the Five Facet Mindfulness Questionnaire (FFMQ), two measures of opioid craving, and the Attention to Positive and Negative Information Scale (APNIS). Across all three samples, dispositional mindfulness was significantly inversely associated with opioid misuse (N = 300, r = -0.36, p < .001). Reduced opioid craving and increased attention to positive information mediated the association between dispositional mindfulness and opioid misuse. Dispositional mindfulness may buffer opioid misuse risk by attenuating opioid craving and enhancing attention to naturally rewarding stimuli.

Comparable studies

Other cross-sectional and survey studies on meditation, most cited first.

Study Year Design Participants
Construct Validity of the Five Facet Mindfulness Questionnaire in Meditating and Nonmeditating Samples Experienced meditators and nonmeditating comparison groups 2008 Cross-sectional study
Neural Correlates of Dispositional Mindfulness During Affect Labeling Adult participants 2007 Observational cross-sectional n = 27
Assessing mindfulness in children and adolescents: Development and validation of the Child and Adolescent Mindfulness Measure (CAMM). School-aged children and adolescents 2011 Cross-sectional validation study n = 1,413
Mindfulness and self-compassion as predictors of psychological wellbeing in long-term meditators and matched nonmeditators Experienced meditators and demographically matched nonmeditators 2012 Cross-sectional study n = 152
Mechanisms of Action in the Inverse Relationship Between Mindfulness and Psychological Distress Undergraduates 2008 Cross-sectional, correlational

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