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Treatment of a Patient With Depersonalization Disorder With Low Frequency Repetitive Transcranial Magnetic Stimulation of the Right Temporo-Parietal Junction in a Private Practice Setting.

Fady Rachid

Journal of Psychiatric Practice March 2017 DOI: 10.1097/pra.0000000000000214 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A 26-year-old man with a 6-month history of depersonalization disorder
Intervention Repetitive transcranial magnetic stimulation
Duration 6-month history of depersonalization disorder
Key findings The authors report that a 26-year-old man with a six-month history of depersonalization disorder responded safely and significantly to repetitive transcranial magnetic stimulation applied to the right temporo-parietal junction, adding to prior case reports of this treatment approach.

Abstract

Depersonalization disorder (DPD) is a debilitating dissociative condition with no proven treatments. Although the pathophysiology of DPD is poorly understood, there are reports of increased excitability of the prefrontal cortex in patients with this condition. The temporo-parietal junction may also play a major role in the conscious experience of the spatial unity of the normal self and body. Repetitive transcranial magnetic stimulation has been shown in some case studies to effectively treat this condition. This report describes an additional such case, a 26-year-old man with a 6-month history of DPD who responded safely and significantly to repetitive transcranial magnetic stimulation to the right temporo-parietal junction.

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