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Meditation for Major Depressive Disorder: A Systematic Review

Melony E. Sorbero, Sangeeta C. Ahluwalia, Kerry A. Reynolds, Susan L. Lovejoy, Coreen A. Farris, Jennifer L. Sloan, Jeremy N. V. Miles, Christine Vaughan, Ryan Kandrack, Eric Apaydin, Benjamin Colaiaco, Patricia M. Herman

RAND Corporation eBooks 2015 DOI: 10.7249/rr1138 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Population Adults with major depressive disorder (MDD)
Intervention Mindfulness-based cognitive therapy
Topics Depression Meditation
Key findings The review synthesized randomized controlled trial evidence on mindfulness-based cognitive therapy, used adjunctively or as monotherapy, to assess its efficacy and safety in adults with major depressive disorder. The abstract states the review's scope but reports no results, effect sizes, or safety outcomes.

Abstract

RAND researchers conducted a systematic review that synthesized evidence from randomized controlled trials of mindfulness-based cognitive therapy — used adjunctively or as monotherapy — to assess its efficacy and safety in treating adults with major depressive disorder (MDD).

Comparable studies

Other systematic reviews and meta-analyses on depression, most cited first.

Study Year Design Participants
Ketamine and Other NMDA Antagonists: Early Clinical Trials and Possible Mechanisms in Depression Participants with major depression in placebo-controlled, double-blind, randomized... 2015 Systematic review and meta-analysis
Side-effects associated with ketamine use in depression: a systematic review. Patients with depression 2018 Systematic review
Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis Adults with unipolar or bipolar major depression 2020 Systematic review and meta-analysis n = 1,877
Single-dose infusion ketamine and non-ketamine N-methyl-D-aspartate receptor antagonists for unipolar and bipolar depression: a meta-analysis of efficacy, safety and time trajectories Patients with major depressive disorder or bipolar depression 2016 Systematic review and meta-analysis n = 588
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188

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Depression Meditation