Effectiveness of group cognitive behavioral therapy with mindfulness in end-stage renal disease hemodialysis patients.
Bo Kyung Sohn, Yun Kyu Oh, Jung-Seok Choi, Jiyoun Song, Ahyoung Lim, Jung Pyo Lee, Jung Nam An, Hee-Jeong Choi, Jae Yeon Hwang, Hee-Yeon Jung, Jun-Young Lee, Chun Soo Lim
Kidney research and clinical practice March 2018 DOI: 10.23876/j.krcp.2018.37.1.77 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pilot study Peer reviewed |
|---|---|
| Sample size | 7 |
| Population | Patients with end-stage renal disease undergoing hemodialysis who were suffering from depression |
| Interventions | Group cognitive behavioral therapy Mindfulness meditation |
| Duration | 12-week intervention; measurements at baseline and weeks 8 and 12; biochemical markers at baseline and 12 weeks |
| Measures | World Health Organization Quality of Life scale, abbreviated version (WHOQOL-BREF), Beck Depression Inventory II (BDI-II), Hamilton Rating Scale for Depression (HAM-D), Beck Anxiety Inventory (BAI), Perceived Stress Scale (PSS), Temperament and Character Inventory |
| Topics | Depression Meditation |
| Keywords | Cognitive behavioral therapy Quality of life Renal dialysis |
| Key points | In seven hemodialysis patients with depression, 12 weeks of group cognitive behavioral therapy including mindfulness meditation was followed by significant improvements in quality of life, mood, anxiety, and perceived stress, with WHOQOL-BREF, BDI-II, and BAI scores improving continuously and HAM-D and PSS scores improving by week 8. Serum creatinine levels also improved significantly after 12 weeks. |
Abstract
Many patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) experience depression. Depression influences patient quality of life (QOL), dialysis compliance, and medical comorbidity. We developed and applied a group cognitive behavioral therapy (CBT) program including mindfulness meditation for ESRD patients undergoing HD, and measured changes in QOL, mood, anxiety, perceived stress, and biochemical markers. We conducted group CBT over a 12-week period with seven ESRD patients undergoing HD and suffering from depression. QOL, mood, anxiety, and perceived stress were measured at baseline and at weeks 8 and 12 using the World Health Organization Quality of Life scale, abbreviated version (WHOQOL-BREF), the Beck Depression Inventory II (BDI-II), the Hamilton Rating Scale for Depression (HAM-D), the Beck Anxiety Inventory (BAI), and the Perceived Stress Scale (PSS). Biochemical markers were measured at baseline and after 12 weeks. The Temperament and Character Inventory was performed to assess patient characteristics before starting group CBT. The seven patients showed significant improvement in QOL, mood, anxiety, and perceived stress after 12 weeks of group CBT. WHOQOL-BREF and the self-rating scales, BDI-II and BAI, showed continuous improvement across the 12-week period. HAM-D scores showed significant improvement by week 8; PSS showed significant improvement after week 8. Serum creatinine levels also improved significantly following the 12 week period. In this pilot study, a CBT program which included mindfulness meditation enhanced overall mental health and biochemical marker levels in ESRD patients undergoing HD.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cited by 6
- Brief Mindfulness Intervention vs. Health Enhancement Program for Patients Undergoing Dialysis: A Randomized Controlled Trial Healthcare June 1, 2021
- The impact of mindfulness meditation on pro-inflammatory biomarkers in patients with end-stage renal disease: A randomized trial SAGE Open Medicine 2024
- Experiences of People with Kidney Disease Following the Implementation of the Compassionate Mindful Resilience Programme: Qualitative Findings from the COSMIC Study. Healthcare November 8, 2023
- Mindfulness-based intervention as a symptom management strategy in patients with end-stage renal disease: A controlled clinical trial. International Journal of Nursing Practice December 1, 2024
- The Role of Mindfulness in Hemodialysis Patients: A Scoping Review Mindfulness September 9, 2026
and 1 more in the library