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Do sex differences in rumination explain sex differences in depression?

Tracey J. Shors, Emma M. Millon, Han Yan M Chang, Ryan L Olson, Brandon L Alderman

Journal of Neuroscience Research January 2, 2017 DOI: 10.1002/jnr.23976 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Intervention study Peer reviewed
Population Adult men and women, most of whom were clinically depressed
Duration 8 weeks of training
Topics Depression Meditation Neuroplasticity
Keywords Exercise Fear Hippocampus Learning Memory Rumination Stress
Key points After eight weeks of MAP Training, both men and women reported significantly fewer depressive symptoms and ruminative thoughts, and depressive symptoms correlated strongly with rumination in both sexes (rho > 0.50). Only in women were depressive symptoms related to "reflective" ruminations, and this relationship was the only one that dissipated after the intervention. The authors suggest the strength of the rumination-depression relationship does not necessarily explain sex differences in depression, but targeting rumination may reduce major depressive disorder, which is more prevalent among women.

Abstract

It is generally accepted that women tend to ruminate more than men do and these thought patterns are often associated with depressive symptoms (Nolen-Hoeksema et al., ). Based on these findings, we considered whether the relationship between rumination and depression is stronger in women than in men and if so, whether this might explain the higher prevalence of major depressive disorder (MDD) in women and finally, whether the association can be disrupted through a mind/body intervention. Adult men and women, most of whom were clinically depressed, participated in an intervention known as MAP Training, which combines "mental" training with silent meditation and "physical" training with aerobic exercise (Shors et al., ). After eight weeks of training, both men and women reported significantly fewer symptoms of depression and fewer ruminative thoughts (Alderman et al., ). Statistical correlations between depressive symptoms and ruminative thoughts were strong and significant (rho > 0.50; p < 0.05) for both men and women before and after MAP Training. However, only in women did depressive symptoms relate to "reflective" ruminations, which involve analyses of past events, feelings, and behaviors. This is also the only relationship that dissipated after the intervention. In general, these analyses suggest that the strength of the relationship between depressive symptoms and rumination does not necessarily explain sex differences in depression; but because the relationship is strong, targeting rumination through intervention can reduce the incidence of MDD, which is more prevalent among women. © 2016 Wiley Periodicals, Inc.

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