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Mindfulness-based interventions for the treatment of depressive rumination: Systematic review and meta-analysis.

Lilisbeth Perestelo-Pérez, Jorge Barraca, Wenceslao Peñate, Amado Rivero-Santana, Yolanda Álvarez-Pérez

International journal of clinical and health psychology : IJCHP 2017 DOI: 10.1016/j.ijchp.2017.07.004 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Peer reviewed
Population Patients with depression
Intervention Mindfulness-based cognitive therapy
Topics Depression Meditation
Keywords Meta-analysis Rumination Systematic review
Key findings Mindfulness-based cognitive therapy reduced ruminative thoughts by a moderate amount compared with usual care (g = -0.59, 95% CI: -0.77, -0.41; I2 = 0%), with the effect maintained one month after treatment and independent of treatment phase or number of past depressive episodes. Comparisons with active treatments (medication, behavioral activation, cognitive-behavioral therapy) showed no significant differences. The authors suggest mindfulness and acceptance processes may mediate changes in rumination, which may in turn mediate clinical effects.

Abstract

Background/Objective: This systematic review aims to evaluate the effect of interventions based on the mindfulness and/or acceptance process on ruminative thoughts, in patients with depression.

Method: Electronic searches in Medline, Embase, Cochrane Central, PsycInfo, and Cinahl until December 2016, in addition to hand-searches of relevant studies, identified eleven studies that fulfilling inclusion criteria.

Results: A meta-analysis of the effect of the intervention compared to usual care showed a significant and moderate reduction of ruminative thoughts (g = -0.59, 95% CI: -0.77, -0.41; I2 = 0%). Furthermore, findings suggest that mindfulness/acceptance processes might mediate changes in rumination, and that they in turn mediate in the clinical effects of interventions. A meta-analysis of three studies that compared the intervention to other active treatments (medication, behavioral activation and cognitive-behavioral therapy, respectively) showed no significant differences.

Conclusions: Mindfulness-based cognitive therapy compared to usual care, produces a significant and moderate reduction in rumination. This effect seems independent of the treatment phase (acute or maintenance) or the number of past depressive episodes, and it was maintained one month after the end of treatment. However, further controlled studies with real patients that compare the most commonly used cognitive-behavioral techniques to treat ruminative thoughts to the acceptance and mindfulness techniques are needed.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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