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Sequential influences of emotion regulation and rumination in trait mindfulness-depression relationships.

G. B. Maruthy, Lyndahl M. Himes, Nicholas A. Hubbard, Jeffrey S Spence, B. Rypma

Journal of Affective Disorders July 1, 2026 DOI: 10.1016/j.jad.2026.122331 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey with structural equation modeling Peer reviewed
Sample size 1,000
Population Undergraduates
Topics Depression Meditation
Key findings Trait mindfulness facets reduce depression symptoms through sequential increases in reappraisal and decreases in brooding rumination, with meditation experience moderating the Nonreact facet's pathway via suppression.

Abstract

Depression is a common mental health disorder affecting millions worldwide. Pharmacotherapies are partially effective, but numerous side effects often make them unfavorable. Recent investigations show that mindfulness meditation effectively mitigates depression-symptoms but the underlying mechanisms remain elusive. Here, we examined the sequential influence of emotion regulation (ER) and rumination tendencies to explore trait mindfulness (TM) effects on depression-symptoms. 1000 undergraduates provided ratings on their depression-symptoms, mindfulness-experience, TM, ER strategy-use and rumination tendencies. Structural equation modeling was used to examine sequential influences of ER strategies and rumination tendencies on TM-depression relationships and how these mechanisms were moderated by meditation-experience. All TM facets showed sequential influences on depression-symptoms through increases in reappraisal and decreases in brooding rumination. Describe, Act with Aware and Nonjudge facets showed additional pathways including reductions in suppression, brooding-rumination and reflective-pondering. The Nonreact facet showed significant influence of meditation-experience on the mediation pathway through suppression. For individuals without meditation-experience there were positive associations between nonreactivity and brooding-rumination, reflective-pondering and depression-symptoms via suppression. These associations were absent in meditation-experienced individuals. Findings suggest the hypothesis that sequential influences of ER strategies and ruminative processes underlie TM-depression relationships and might have implications for how TM facets influence ER and rumination to promote or mitigate depression.