[Visual Impairment and False Perceptions in Dementia with Lewy Bodies].
Yoshiyuki Nishio
Brain and nerve = Shinkei kenkyu no shinpo August 2018 DOI: 10.11477/mf.1416201098 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Key findings | Argues that while visual impairment in dementia with Lewy bodies is explicable as functional damage to the visual cortices, visual hallucinations lack a compelling explanation, and proposes that false perceptions may be a behavioral consequence of an aberrant cortical state caused by cholinergic insufficiency. |
Abstract
Visual impairment and visual hallucinations are diagnostic signposts of dementia with Lewy bodies (DLB). Visual impairment is easily explicable as a functional impairment that results from damage to the visual cortices, whereas there is currently no compelling explanations for the mechanisms of visual hallucinations and other false perceptions. Here, I review evidence regarding the phenomenology and mechanisms of false perceptions in DLB, and propose that false perceptions maybe behavioral consequence of aberrant cortical state caused by cholinergic insufficiency.