Cognitive motor deficits in cannabis users
Shikha Prashad, Francesca Mapua Filbey
Current Opinion in Behavioral Sciences July 19, 2016 DOI: 10.1016/j.cobeha.2016.07.001 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Cannabis |
| Citations | 49 |
| Key findings | The authors report that cannabis use is associated with motor performance impairments, but note a gap in research on motor learning. They argue that because cortico-striatal networks are involved in both cannabis addiction and movement, the motor system may provide avenues for treatment and rehabilitation. |
Abstract
Cannabis use affects cortico-striatal networks that are essential for producing movement. In this review, we summarize the literature on motor system dysfunction in cannabis users and provide a rationale for why motor learning should be considered an important area in cannabis research. A majority of studies have addressed cognitive impairments in cannabis users and some have focused on driving performance, motor impulsivity, and motor inhibition. Our review of the literature has found that cannabis use is associated with motor performance impairments; however, there is a gap in the literature regarding impairments in motor learning. The involvement of the cortico-striatal network in both cannabis addiction and movement also suggests potential avenues for treatment and rehabilitation via the motor system.
Comparable studies
Other narrative reviews on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Causal association between cannabis and psychosis: examination of the evidence | 2004 | Review | |
| Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history. General (historical and pharmacological review) | 2018 | Review | |
| Psychiatric effects of cannabis | 2001 | Review | |
| Beyond THC: The New Generation of Cannabinoid Designer Drugs | 2011 | Review | |
| Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug | 2006 | Review |
Citations in the library
Cited by 7
- Disruption of Reelin signaling in a dual-hit mouse model of schizophrenia: impact of postnatal Δ9-tetrahydrocannabinol exposure in a maternal immune activation model Translational Psychiatry July 16, 2026
- Cognitive Effects of Cannabis Use: A Comprehensive Review Across Domains Neurology International July 1, 2025
- Chronic Δ9-tetrahydrocannabinol treatment has dose-dependent effects on open field exploratory behavior and [3H] SR141716A receptor binding in the rat brain. Life Sciences August 15, 2023
- Chronic use of cannabis might impair sensory error processing in the cerebellum through endocannabinoid dysregulation. Addictive Behaviors August 2022
- Cannabis induced increase in striatal glutamate associated with loss of functional corticostriatal connectivity. European Neuropsychopharmacology December 1, 2019
and 2 more in the library
Cites 10
- Tolerance and cross-tolerance to neurocognitive effects of THC and alcohol in heavy cannabis users Psychopharmacology October 30, 2010
- Smoked Cannabis' Psychomotor and Neurocognitive Effects in Occasional and Frequent Smokers Journal of Analytical Toxicology March 4, 2015
- Altered brain activation during visuomotor integration in chronic active cannabis users: relationship to cortisol levels. Journal of Neuroscience December 7, 2011
- Neuropsychological deficits associated with cannabis use in young adults Drug and Alcohol Dependence September 14, 2011
- Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Delta-9-tetrahydrocannabinol in humans. Psychopharmacology July 2008
and 5 more in the library