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Comparing triggers to visual disturbances among individuals with positive vs negative experiences of hallucinogen-persisting perception disorder (HPPD) following LSD use.

Shaul Lev-Ran, Daniel Feingold, Craig Goodman, Arturo G Lerner

American Journal on Addictions September 2017 DOI: 10.1111/ajad.12577 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study using clinical questionnaires Peer reviewed
Sample size 40
Population Individuals with HPPD and prior LSD use
Topics LSD
Key findings Among 40 people with HPPD and prior LSD use, Type I was most commonly marked by slow movement of still objects and Type II by trailing phenomena. Type I was more often associated with disturbances in dark environments, while looking at a still or moving object, and during sexual intercourse. The authors propose the subtypes may be different phenomena on the same spectrum and call for further research.

Abstract

Exploring differences in visual disturbances and triggers between Hallucinogen-Persisting-Perceptual-Disorder (HPPD) Type I ("positive/benign") and II ("negative/distressing"). Forty individuals with HPPD and prior LSD use completed clinical questionnaires. The most common type of visual disturbances among individuals with HPPD I and II was slow movement of still objects and trailing phenomena, respectively. Those with HPPD I were more likely to report experiencing disturbances in dark environment, while looking at a still or moving object and during sexual intercourse. HPPD I and II differ in terms of visual disturbances and triggers, possibly representing different phenomena existing on the same spectrum. Our study indicating differences in triggers to HPPD I and II adds to existing literature on differences in visual disturbances between the two subtypes. Further research elucidating additional differences between the subtypes of HPPD is needed. (Am J Addict 2017;26:568-571).

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Patterns of recreational drug use at dance events in Edinburgh, Scotland Drug users at dance events in Edinburgh, Scotland, UK, aged 16-47, 80% between 18 and... 2001 Cross-sectional survey n = 122
Development of the Psychological Insight Questionnaire among a sample of people who have consumed psilocybin or LSD Psilocybin and LSD users 2021 Cross-sectional survey study n = 1,661
Prevalence and associations of challenging, difficult or distressing experiences using classic psychedelics. US adult population 2023 Cross-sectional survey n = 2,822
Trends in LSD use among US adults: 2015-2018. US adults ages 18 and older 2020 Secondary analysis of cross-sectional survey data n = 168,562

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