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Effects of Mindfulness-Based Cognitive Therapy on Anxiety Sensitivity in Patients with Multiple Sclerosis

Mahtab Dizaj Khalili, Shahrokh Makvand Hosseini, P. Sabahi

Jundishapur Journal of Chronic Disease Care March 3, 2023 DOI: 10.5812/jjcdc-132672 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Quasi-experimental pretest-posttest control group design with follow-up Peer reviewed
Sample size 30
Population Women with multiple sclerosis enrolled in the Tehran MS Society
Intervention Mindfulness-based cognitive therapy (MBCT)
Duration Eight 90-minute sessions; follow-up period (duration not specified)
Measures Anxiety Sensitivity Index (ASI)
Topics Anxiety Meditation
Key findings Mindfulness-based cognitive therapy significantly reduced anxiety sensitivity in women with MS compared with a no-treatment control group, with lower scores at posttest and maintained at follow-up (P < 0.001). The authors conclude MBCT may be an effective intervention for anxiety sensitivity in this population.

Abstract

Background: Multiple sclerosis (MS) is a chronic condition that can seriously impact a patient’s functions and quality of life. Mindfulness-based meditation as a clinical intervention can positively affect the emotional and physical states of patients with MS.

Objectives: The present study aimed to investigate the role of mindfulness-based cognitive therapy (MBCT) on anxiety sensitivity in patients with MS.

Methods: This quasi-experimental study adopted a pretest-posttest, control group design with follow-up. The statistical population included the women with MS who enrolled in the Tehran MS Society. Convenience sampling was employed to select 30 participants who were assigned randomly to an experimental group and a control group (15 members per group). The experimental group received MBCT (for eight 90-minute sessions), whereas the control group received no interventions. The Anxiety Sensitivity Index (ASI) was used for data collection, and repeated measures ANCOVA was adopted for data analysis.

Results: The mean age of women was 37.21 ± 5.78 years. Also, the duration of the disease in the participants was 5.81 ± 2.43 years. The mean ± standard deviation (SD) of the pretest, posttest, and follow-up scores of anxiety sensitivity in the experimental group were101.66 ± 2.63, 93.86 ± 3.11 and 94.00 ± 3.62, respectively, which in the posttest and follow-up was significantly different from the control groups (P < 0.001). The MBCT significantly improved anxiety sensitivity components in the experimental group compared to the control group. This significant difference was also observed during the follow-up period (P < 0.001).

Conclusions: The MBCT helped alleviate anxiety sensitivity in women with MS. Therefore, psychotherapists can use MBCT as an effective intervention in improving anxiety sensitivity in women with MS.

Comparable studies

Other experimental studies on anxiety, most cited first.

Study Year Design Participants
A PILOT STUDY OF GROUP MINDFULNESS-BASED COGNITIVE THERAPY (MBCT) FOR COMBAT VETERANS WITH POSTTRAUMATIC STRESS DISORDER (PTSD) Veterans with chronic combat posttraumatic stress disorder seeking treatment at a VA... 2013 Quasi-experimental with treatment-as-usual comparison group n = 37
Being present in the face of existential threat: The role of trait mindfulness in reducing defensive responses to mortality salience. 2010 Experimental study
Neural correlates of mindfulness meditation-related anxiety relief Healthy adults with no prior meditation experience 2013 Within-subjects experimental study n = 15
Intensive mindfulness training-related changes in cognitive and emotional experience Community adults 2009 Quasi-experimental and longitudinal n = 69
Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: effects on salivary IL-6, cortisol levels, affect, and non-judgment Volunteers 2019 Within-subjects experimental study n = 11

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