Improvement of Tardive Dyskinesia during Mindfulness Meditation.
Maria Angela Santoro, Isolde English, Idil Sezer, Mickael Amagat, Frank Ly, Edouard Chaneac, Patricia Cailliez, Hugo Bottemanne
Neurology International August 30, 2021 DOI: 10.3390/neurolint13030043 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A patient with orofacial tardive dyskinesia following loxapine administration |
| Interventions | Mindfulness-based cognitive therapy (MBCT) Mindfulness-based stress reduction (MBSR) |
| Duration | 4 weeks of repeated sessions |
| Measures | Abnormal Involuntary Movement Scale (AIMS) |
| Topics | Meditation |
| Keywords | Dyskinesia Dystonia Mindfulness meditation Mindfulness-based cognitive therapy Movement disorder |
| Key findings | The authors report that four weeks of repeated mindfulness-based cognitive therapy and mindfulness-based stress reduction sessions were followed by quantitative and qualitative improvement in orofacial tardive dyskinesia, both during sessions and at rest long term, with complete arrest of the dyskinesia in some sessions where compliance was rated maximal. They suggest mindfulness meditation as a novel adjunctive therapeutic approach and call for further clinical and neurological investigation. |
Abstract
We report the case of a patient presenting with orofacial tardive dyskinesia (TD), following administration of a first-generation antipsychotic (Loxapine). Four weeks of repeated sessions of mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) protocols were administered, with TD hetero-quantified before and during each session via the Abnormal Involuntary Movement Scale (AIMS). The dyskinesia ameliorated quantitatively and qualitatively (1) during each session, and (2) at resting conditions in the long term. During some sessions, after which patients' compliance was auto-evaluated as maximal, complete arrest of the TD was observed. Hypothesis and Conclusion: We suggest mindfulness meditation as a novel adjunctive therapeutic approach for tardive dyskinesia, and invite for further clinical and neurological investigations.
Comparable studies
Other case reports and case series on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Brain sources of EEG gamma frequency during volitionally meditation-induced, altered states of consciousness, and experience of the self Advanced meditator | 2001 | Case study | n = 1 |
| Mindfulness Meditation for Alcohol Relapse Prevention: A Feasibility Pilot Study Adult alcohol-dependent graduates of an intensive outpatient program | 2008 | Prospective case series | n = 19 |
| How does it feel to lack a sense of boundaries? A case study of a long-term mindfulness meditator. A single long-term mindfulness practitioner (S) with 40 years of practice in... | 2015 | Qualitative case study | n = 1 |
| Loving‐kindness meditation to enhance recovery from negative symptoms of schizophrenia Individuals suffering from schizophrenia-spectrum disorders with persistent negative... | 2009 | Case study | |
| Mindfulness-Based Cognitive Therapy for Problem Gambling A female problem gambler | 2011 | Case study | n = 1 |
Citations in the library
Cites 7
- Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network Cerebral Cortex April 9, 2008
- Meditation experience is associated with increased cortical thickness Neuroreport November 7, 2005
- Short-term meditation training improves attention and self-regulation Proceedings of the National Academy of Sciences October 11, 2007
- Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Proceedings of the National Academy of Sciences November 8, 2004
- Mindfulness Meditation and Psychopathology Annual Review of Clinical Psychology December 11, 2018
and 2 more in the library