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Executive Functions and Cannabis Use in Adolescents

Alessandro Frolli, Maria Carla Ricci, Antonella Cavallaro, Agnese Lombardi, Grazia Maria Giovanna Pastorino, Francesca Felicia Operto

Preprints.org July 22, 2020 preprint DOI: 10.20944/preprints202007.0499.v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study
Population Adolescents grouped by cannabis use: chronic users, occasional users, and non-users
Topics Cannabis
Citations 3
Key findings The group using chronic cannabis showed a significant drop in working memory tasks compared with the group that did not use cannabis. The authors also state that most human research links chronic cannabis abuse to impaired divided attention, verbal memory, and working memory.

Abstract

The developmental phase of adolescence is characterized by a multitude of neurocognitive and psychosocial changes and is therefore considered one of the most critical developmental periods of life. Experimentation on the use of substances often begins in adolescence and so does the addiction process. Most research in human subjects shows that chronic cannabis abuse is the cause of the impairment of some cognitive functions, affecting the performance on divided attention, verbal memory and working memory. In this study, we wanted to investigate how the abuse of cannabis (chronic, occasional and absence use) can influence global cognitive functioning, also through executive functions. From the statistical analyzes of our study, it emerges that the group of subjects who use chronic cannabis (group 1) has a significant drop in working memory tasks compared to the group that does not use it (group 3). In addition, the goal of future studies by our group is to verify the permanent alteration of cognitive processes affected through revaluations with calendar follow-up (controlled).

Comparable studies

Other observational and cohort studies on cannabis, most cited first.

Study Year Design Participants
High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population 2009 Case-control study n = 454
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people 2000 Observational
Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline 2011 Observational cohort n = 1,923
Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... 2005 Observational cohort n = 535

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