Novel Pyrrolopyridine Compounds as 5-HT2A Agonists for Treating Mental Illnesses.
Ram W. Sabnis, Anika R. Sabnis
ACS Medicinal Chemistry Letters January 23, 2025 DOI: 10.1021/acsmedchemlett.5c00019 (opens in new tab)
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AI-extracted from the abstract| Characteristics | Peer reviewed |
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Abstract
Provided herein are novel pyrrolopyridine compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mental illnesses, and processes for preparing such compounds.
Citations in the library
Cites 5
- Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants Chemical Reviews November 30, 2023
- Antidepressant and anxiolytic effects of activating 5HT2A receptors in the anterior cingulate cortex and the theoretical mechanisms underlying them - A scoping review of available literature. Brain Research 2025
- 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI): From an Obscure to Pivotal Member of the DOX Family of Serotonergic Psychedelic Agents - A Review. ACS Pharmacology & Translational Science June 14, 2024
- Psychedelic therapy in depression and substance use disorders European Journal of Neuroscience May 21, 2024
- Novel 3-Pyrrolidineindole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis and Mental Illnesses Such as Depression and Post-Traumatic Stress Disorder. ACS Medicinal Chemistry Letters January 9, 2025