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Novel 3-Pyrrolidineindole Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis and Mental Illnesses Such as Depression and Post-Traumatic Stress Disorder.

Ram W. Sabnis

ACS Medicinal Chemistry Letters January 9, 2025 DOI: 10.1021/acsmedchemlett.4c00581 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Peer reviewed
Topics Depression PTSD Serotonin
Citations 7
Key points Novel 3-pyrrolidineindole derivatives act as serotonergic psychedelic agents with potential to treat depression, post-traumatic stress disorder, and psychosis.

Abstract

Provided herein are novel 3-pyrrolidineindole derivatives as serotonergic psychedelic agents, pharmaceutical compositions, use of such compounds in treating psychosis and mental illnesses such as depression and post-traumatic stress disorder, and processes for preparing such compounds.