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Are the current safety measures for the treatment of depression with esketamine sufficient?

Kyle Valentino, Kayla M Teopiz, Christine E Dri, Jennifer Swainson, Yang Jing Zheng, Roger S McIntyre

Expert Opinion on Drug Safety February 19, 2026 DOI: 10.1080/14740338.2026.2627184 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Peer reviewed
Topics Depression Esketamine Ketamine
Keywords Rems

Abstract

1. Esketamine as monotherapy or adjunct to conventional antidepressants is proven efficacious in clinical trials in adults with treatment-resistant depression (TRD) and depression with high risk of...

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