The Synthesis of Four Possible in vitro Metabolites of the Hallucinogen 1-(2,5-Dimethoxy-4-methylphenyl)-2-aminopropane (DOM)
Ronald T. Coutts, Jerry L. Malicky
Canadian Journal of Chemistry February 1, 1974 DOI: 10.1139/v74-063 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
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| Key points | The authors report the synthesis of four compounds they propose as possible in vitro metabolites of DOM, formed by side chain metabolic oxidation: 1-(2,5-dimethoxy-4-methylphenyl)-2-propanone, its oxime, 1-(2,5-dimethoxy-4-methylphenyl)-2-propanol, and 1-(2,5-dimethoxy-4-methylphenyl)-2-(hydroxylamino)propane. No biological activity or metabolic data are presented. |
Abstract
The synthesis of four possible in vitro metabolites of the hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) is described. These compounds, 1-(2,5-dimethoxy-4-methylphenyl(-2-propanone, the corresponding oxime, 1-(2,5-dimethoxy-4-methylphenyl)-2-propanol, and 1-(2,5-dimethoxy)-4-methylphenyl-2-(hydroxylamino)propane, could be products of side chain metabolic oxidation of DOM.
Citations in the library
Cited by 2
- Synthesis of deuterium‐labelled standards of (±)‐DOM and (±)‐MMDA Journal of Labelled Compounds and Radiopharmaceuticals June 1, 2007
- ChemInform Abstract: THE SYNTHESIS OF FOUR POSSIBLE IN VITRO METABOLITES OF THE HALLUCINOGEN 1‐(2,5‐DIMETHOXY‐4‐METHYLPHENYL)‐2‐AMINOPROPANE (DOM) Chemischer Informationsdienst April 30, 1974