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Effects of transcendental meditation on symptoms and electrocardiographic changes in patients with cardiac syndrome X.

C Cunningham, S Brown, J C Kaski

The American journal of cardiology March 1, 2000 DOI: 10.1016/s0002-9149(99)00828-0 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Sample size 9
Population Women with chest pain and normal coronary angiograms
Intervention Transcendental meditation
Duration 3 months
Topics Meditation
Key findings Transcendental meditation significantly improved exercise tolerance, angina episodes, and quality of life in nine women with chest pain and normal coronary angiograms, suggesting potential benefit but requiring further research.

Abstract

Chest pain with normal coronary angiograms is often associated with chronic sympathetic activation, anxiety, and depression, and is resistant to conventional antianginal treatment. The practice of transcendental meditation, a standard relaxation method for 3 months twice daily, significantly improved exercise tolerance, angina episodes, and quality of life in 9 women; the positive findings in this study warrant further research.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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