Mindfulness-based cognitive therapy vs cognitive behaviour therapy as a treatment for non-melancholic depression.

Study at a glance

Characteristics	Randomized controlled trial Peer reviewed
Population	Adults with non-melancholic depression
Interventions	Mindfulness-based cognitive therapy Cognitive behaviour therapy
Topics	Depression Meditation
Key findings	Both MBCT and CBT significantly reduced depressive symptoms, with no significant difference between the two treatments at post-treatment or follow-up. The authors suggest MBCT is a viable alternative to CBT for non-melancholic depression.

Other randomized controlled trials on depression, most cited first.

Study	Year	Design	Participants
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression Subjects with DSM-IV major depression (treatment resistant)	2006	Randomized, placebo-controlled, double-blind crossover study	n = 18
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients	2000	Randomized controlled trial	n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety	2016	Randomized controlled trial	n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression	2016	Double-blind, placebo-controlled, crossover trial	n = 29
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients	2004	Randomized controlled trial	n = 73