Environmental influences on activity patterns in altered states of consciousness
A.-S. de Weer, M. da Ros, Jacques Berré, Christian Mélot, Serge Goldman, Philippe Peigneux
European Journal of Neurology July 19, 2011 DOI: 10.1111/j.1468-1331.2011.03477.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 4 |
| Population | Patients with disorders of consciousness (traumatic and anoxic-ischaemic) |
| Duration | 4-9 days |
| Topics | Altered states of consciousness |
| Citations | 15 |
| Key findings | Light variations correlated with motor activity in all four patients, but day-night motor activity differences and correlation with social environmental changes were found only in the two traumatic minimally conscious state patients. Rapid light variations may temporarily promote arousal in all disorders of consciousness. |
Abstract
Background: AND
Purpose: To evaluate in disorders of consciousness (DOC) circadian variations in motor patterns and their possible synchronization with physiologically regulated light variations and/or a social environmental factor, i.e. presence and actions of other persons.
Methods: Actimetric and ambient light levels recordings were obtained during 4-9 days in two patients with traumatic brain injury (TB1 and TB2) in a minimally conscious state (MCS), one MCS (AI1) and one comatose (AI2) anoxic-ischaemic patients. Environmental changes were automatically recorded using a video system.
Results: Minute light variations correlated with motor activity in all patients. However, motor activity was significantly higher during day than nighttime and correlated with social environmental changes, in patients TB1 and TB2 only.
Conclusions: Night-day circadian variations in motor activity patterns and influence of social stimulations were observed in traumatic MCS patients only. Nonetheless, rapid light variations may temporarily promote increased arousal, and consequently motor activity, in all DOCs.
Comparable studies
Other observational and cohort studies on altered states of consciousness, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Neural correlates of the DMT experience assessed with multivariate EEG. 6 female, 7 male human participants | 2019 | Observational cohort | n = 13 |
| Measures of entropy and complexity in altered states of consciousness Subjects during resting wakefulness, different sleep stages, and epileptic seizures | 2017 | Observational study | |
| Altered States of Consciousness and Short-Term Psychological After-Effects Induced by the First Time Ritual Use of Ayahuasca in an Urban Context in Brazil First-time ayahuasca users in Santo Daime and União do Vegetal rituals | 2005 | Observational cohort | n = 28 |
| Quantifying arousal and awareness in altered states of consciousness using interpretable deep learning Healthy individuals during sleep, individuals under general anesthesia, and patients... | 2022 | Observational cohort | n = 71 |
| Subanaesthetic ketamine and altered states of consciousness in humans Human volunteers | 2018 | Observational study | n = 15 |