Causes and effects of cellular oxidative stress as a result of MDMA abuse.
Current Pharmaceutical Biotechnology August 1, 2010 DOI: 10.2174/138920110791591544 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA |
| Key findings | Argues that MDMA abuse causes cellular oxidative stress via dopamine metabolism and mitochondrial dysfunction, leading to neurotoxicity and long-term cognitive deficits. Proposes that antioxidants may mitigate these effects. |
Abstract
Causes and effects of cellular oxidative stress as a result of MDMA abuse.
Comparable studies
Other narrative reviews on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Human Pharmacology of MDMA | 2004 | Review | |
| Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research | 2001 | Review | |
| 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans | 1994 | Review | |
| (±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals | 2000 | Review | |
| Amphetamine toxicities | 2010 | Review |
Citations in the library
Cited by 2
- MDMA & Cannabis: A Mini-Review of Cognitive, Behavioral, and Neurobiological Effects of Co-Consumption Current Drug Abuse Reviews June 1, 2011
- Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver. Pharmacological Research August 12, 2011