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Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver.

Pharmacol Res August 12, 2011 DOI: 10.1016/j.phrs.2011.08.002 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Experimental study Peer reviewed
Population Rats
Intervention MDMA
Duration Acute administration
Topics MDMA
Key findings Acute MDMA administration induces oxidative stress, lipoperoxidation, and TNFα-mediated apoptosis in rat liver.

Abstract

Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver.