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The paradox of right dorsolateral prefrontal cortex targeting: why did low-frequency repetitive transcranial magnetic stimulation modulate default mode network but not frontoparietal network BOLD-CSF coupling in chronic insomnia?

Sleep August 1, 2026 DOI: 10.1093/sleep/zsag056 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Commentary Peer reviewed
Topics Default mode network
Key points Argues that low-frequency rTMS over the right dorsolateral prefrontal cortex modulates BOLD-CSF coupling in the default mode network but not the frontoparietal network, and proposes that this differential effect may arise from network-specific connectivity and stimulation parameters, suggesting the need for refined targeting.

Abstract

The paradox of right dorsolateral prefrontal cortex targeting: why did low-frequency repetitive transcranial magnetic stimulation modulate default mode network but not frontoparietal network BOLD-CSF coupling in chronic insomnia?

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