Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidence.
Neurosci Biobehav Rev August 14, 2026 DOI: 10.1016/j.neubiorev.2026.106911 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Peer reviewed |
|---|---|
| Topics | Esketamine Ketamine MDMA |
| Key findings | The review indicates that classic psychedelics, MDMA, and ketamine do not cause lasting cognitive impairment, and some studies suggest potential improvements in cognitive flexibility and well-being, though evidence is limited by methodological heterogeneity. |
Abstract
Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidence.