Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review
Aryan Sarparast, Kelan Thomas, Benjamin Malcolm, Christopher S. Stauffer
Psychopharmacology March 7, 2022 DOI: 10.1007/s00213-022-06083-y (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Peer reviewed |
|---|---|
| Topics | MDMA Psilocybin |
| Keywords | Hallucinogen Psychoactive drug Pharmacology |
| Citations | 85 |
| Key findings | Psychiatric drugs, particularly serotonergic medications like SSRIs, can alter the effects and safety profile of MDMA and psilocybin, necessitating careful management during psychedelic-assisted therapy. |
Abstract
As MDMA and psilocybin continue to move through the FDA drug development process, this systematic review offers a compilation of existing research on psychiatric drug-drug interactions with MDMA or psilocybin.