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The effectiveness of mindfulness-based stress reduction (MBSR) in anxiety and depression in patients with multiple sclerosis (MS)

E. Alisaleh, S. Ghahari

European Psychiatry April 1, 2017 DOI: 10.1016/j.eurpsy.2017.01.343 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Semi-experimental pretest-posttest with control group Peer reviewed
Sample size 30
Population Patients with multiple sclerosis referred to Iran MS Association
Intervention Mindfulness-based stress reduction
Duration 8 sessions
Topics Anxiety Depression Meditation
Key findings Mindfulness-based stress reduction significantly reduced anxiety and depression in MS patients compared with a wait-list control group (P < 0.001).

Abstract

ObjectiveThe main objective of the present study is to investigate effectiveness of mindfulness-based stress reduction in anxiety and depression in patients with multiple sclerosis.MethodsThis study is in kind of semi-experimental research in form of pretest–posttest pattern with control group. Statistical population of the study consists of all patients with multiple sclerosis referred to Iran MS Association by 2016. Sampling method in this study is available sampling and based on having inclusion criteria. Among depressed and anxiety patients 30 individuals were selected randomly and were classified in two groups with 15 people in each group. Experimental group was under mindfulness-based training on stress reduction for 8 sessions. Control group was also in waiting list. All patients in experimental and control groups fulfilled depression and anxiety inventories before and after intervention. Obtained data was analyzed using MANCOVA and in SPSS22 software.FindingObtained results show that there is significant difference between the two groups in terms of anxiety and depression after intervention (P < 0.001).ConclusionMindfulness-based stress reduction can help reduction of symptoms of anxiety and depression in patients with MS.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Comparable studies

Other experimental studies on anxiety, most cited first.

Study Year Design Participants
A PILOT STUDY OF GROUP MINDFULNESS-BASED COGNITIVE THERAPY (MBCT) FOR COMBAT VETERANS WITH POSTTRAUMATIC STRESS DISORDER (PTSD) Veterans with chronic combat posttraumatic stress disorder seeking treatment at a VA... 2013 Quasi-experimental with treatment-as-usual comparison group n = 37
Being present in the face of existential threat: The role of trait mindfulness in reducing defensive responses to mortality salience. 2010 Experimental study
Neural correlates of mindfulness meditation-related anxiety relief Healthy adults with no prior meditation experience 2013 Within-subjects experimental study n = 15
Intensive mindfulness training-related changes in cognitive and emotional experience Community adults 2009 Quasi-experimental and longitudinal n = 69
Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: effects on salivary IL-6, cortisol levels, affect, and non-judgment Volunteers 2019 Within-subjects experimental study n = 11

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