LSD and psilocybin flatten the brain’s energy landscape: insights from receptor-informed network control theory
bioRxiv May 17, 2021 preprint DOI: 10.1101/2021.05.14.444193 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper |
|---|---|
| Topics | LSD Psilocybin |
| Key points | Argues that LSD and psilocybin flatten the brain's energy landscape, reducing the stability of brain states and facilitating transitions between them, potentially explaining their psychedelic effects. |
Abstract
LSD and psilocybin flatten the brain’s energy landscape: insights from receptor-informed network control theory
Comparable studies
Other theoretical and historical papers on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The Experimental Use of Psychedelic (LSD) Psychotherapy | 1970 | Historical analysis | |
| LSD: My Problem Child | 1981 | Historical analysis | |
| On the Use and Abuse of LSD | 1968 | Theoretical or philosophical paper | |
| The Use of Music in Psychedelic (LSD) Psychotherapy | 1972 | Theoretical or philosophical paper | |
| Flashbacks: Recurrent Intrusive Images After the Use of LSD | 1969 | Theoretical or philosophical paper |
Citations in the library
Cited by 13
- Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Journal of Psychopharmacology February 2, 2022
- Psychedelic perceptions: mental health service user attitudes to psilocybin therapy Irish Journal of Medical Science June 15, 2021
- A complex systems perspective on psychedelic brain action. Trends in Cognitive Sciences February 3, 2023
- Pattern breaking: a complex systems approach to psychedelic medicine Neuroscience of Consciousness 2023
- Prefrontal contributions to the stability and variability of thought and conscious experience Neuropsychopharmacology September 20, 2021
and 8 more in the library
Cites 39
- A default mode of brain function Proceedings of the National Academy of Sciences January 16, 2001
- The Brain's Default Mode Network Annual Review of Neuroscience May 4, 2015
- The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs Frontiers in Human Neuroscience 2014
- Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin Proceedings of the National Academy of Sciences January 23, 2012
- REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics Pharmacological Reviews June 20, 2019
and 34 more in the library