High spirituality may be associated with right hemispheric lateralization in Korean adults living with epilepsy.
Sang-Ahm Lee, Myung-Ah Ko, Eun-Ju Choi, Ji-Ye Jeon, Han Uk Ryu
Epilepsy & behavior : E&B November 1, 2017 DOI: 10.1016/j.yebeh.2017.08.033 (opens in new tab) via PubMed
Summary
AI-generated from the abstractIn Korean adults with epilepsy, high spirituality is associated with right hemispheric lateralization of the seizure onset zone, but not with temporal lobe involvement. Among 180 participants, 51.1% scored above the median on a spirituality scale. Univariate analyses linked high spirituality to female sex, older age, longer epilepsy duration, polytherapy, complex partial seizures, and use of levetiracetam or topiramate, but multiple logistic regression identified right hemispheric lateralization as the only independent factor (odds ratio: 2.410).
Study at a glance
| Characteristics | Cross-sectional study Peer reviewed |
|---|---|
| Sample size | 180 |
| Population | Korean adults living with epilepsy |
| Keywords | Epilepsy Religion Religious experience Right hemispheric lateralization Spirituality |
| Key finding | Right hemispheric lateralization of the seizure onset zone was the only independent factor associated with high spirituality. |
Abstract
Although it is known that epilepsy and spirituality are related, spirituality in epilepsy has received relatively little clinical and scientific attention. Therefore, we investigated which epilepsy-related factors are associated with high spirituality in Korean adults living with epilepsy. This cross-sectional study was conducted in two university hospitals in Korea. Spirituality was assessed using the 6-item Spirituality Self-Rating Scale (SSRS). The participants were categorized into high and low spirituality groups according to the median SSRS score. The presumptive seizure onset zone was determined based on the clinical semiology, electroencephalography, and magnetic resonance imaging findings. Of the 180 participants, 61.7% declared that they had a religious affiliation. The median SSRS score was 15 (interquartile range: 7, 22). The high spirituality subgroup consisted of 92 (51.1%) participants. In the univariate analyses, the high spirituality group was significantly associated with female sex (p<0.05), older age (p<0.01), longer epilepsy duration (p<0.05), polytherapy (p<0.05), complex partial seizure (p<0.05), levetiracetam or topiramate usage (p<0.05), and a right-lateralized seizure onset zone. The multiple logistic regression analysis identified right hemispheric lateralization as the only independent factor associated with high spirituality (odds ratio: 2.410, 95% confidence interval: 1.051-5.528, p<0.05). High spirituality may be associated with right hemispheric lateralization but not with the temporal localization of the seizure onset zone in Korean adults with epilepsy.