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Understanding treatment expectations toward emerging therapies in veterinary medicine: the role of knowledge, attitudes, and beliefs toward psychedelic-assisted interventions

Yanira Suárez-Fernández, Elisa Hernández-Álvarez, Lucas F Borkel, Jaime Rojas-Hernández, Domingo J Quintana-Hernández, Luis Alberto Henríquez-Hernández

Frontiers in Veterinary Science July 28, 2026 DOI: 10.3389/fvets.2026.1864343 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey Longitudinal Peer reviewed
Sample size 87
Population Undergraduate veterinary students at the University of Las Palmas de Gran Canaria
Topics Psychedelic-assisted therapy
Keywords Animal welfare Risk perception Treatment expectations Veterinary students
Key findings Positive attitudes toward psychedelics were the strongest and most consistent predictor of favorable treatment expectations for psychedelic-assisted therapies among veterinary students.

Abstract

IntroductionThe adoption of emerging therapeutic approaches in veterinary medicine is likely to depend not only on scientific evidence but also on how such interventions are cognitively and attitudinally appraised by future professionals. This study aimed to assess knowledge, attitudes, and perceived risk regarding psychedelic use among veterinary students, and to examine their association with treatment expectations toward psychedelic-assisted therapies.MethodsA cross-sectional survey was conducted among undergraduate veterinary students (N = 87) at the University of Las Palmas de Gran Canaria during the 2025/2026 academic year. Data were collected using a structured questionnaire assessing knowledge and beliefs about psychedelics, alongside the Treatment Expectation Questionnaire (TEX-Q). Exploratory factor analysis identified two latent dimensions—positive attitudes and perceived risk—which were included as independent variables in subsequent analyses. Associations were examined using nonparametric tests, correlation analyses, and multiple linear regression models.ResultsPositive attitudes showed the strongest and most consistent associations with favorable expectation domains, including perceived treatment benefit, impact, and overall expectations, while perceived risk showed an inverse, though more moderate, pattern of associations. Sociodemographic and educational variables were more closely associated with treatment expectations through these psychological constructs than through direct associations with the expectation domains themselves.DiscussionThese findings are consistent with a cognitive–attitudinal framework in which expectations toward emerging therapies are more closely associated with interpretable psychological dimensions rather than with factual knowledge alone. Future longitudinal studies are warranted to clarify the relationships among these variables and to evaluate how educational experiences influence their development.

Comparable studies

Other cross-sectional and survey studies on psychedelic-assisted therapy, most cited first.

Study Year Design Participants
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic 2020 Cross-sectional survey n = 985
Psychedelic Treatment for Trauma-Related Psychological and Cognitive Impairment Among US Special Operations Forces Veterans U.S. Special Operations Forces Veterans who completed a psychedelic clinical program in... 2020 Survey n = 51
Population Survey Data Informing the Therapeutic Potential of Classic and Novel Phenethylamine, Tryptamine, and Lysergamide Psychedelics Respondents from the National Survey on Drug Use and Health, 2008–2017, weighted to... 2020 Cross-sectional survey n = 260,964,827
Examination of the Phenomenology of the Ibogaine Treatment Experience: Role of Altered States of Consciousness and Psychedelic Experiences. Individuals who used ibogaine in the past 2017 Retrospective survey n = 27
American Psychiatrists' Opinions About Classic Hallucinogens and Their Potential Therapeutic Applications: A 7-Year Follow-Up Survey. American Psychiatric Association members (resident-fellows and attending psychiatrists) 2024 Survey n = 131

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